Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple
organs. A complex interaction of genetics, environment, and hormones leads to immune …

Objective To define candidate criteria within multiphase development of systemic lupus
erythematosus (SLE) classification criteria, jointly supported by the American College of …

Autoimmune connective tissue diseases arise in a stepwise fashion from asymptomatic
preclinical autoimmunity. Type I interferons have a crucial role in the progression to …

Systemic Lupus Erythematosus (SLE) is a complex chronic autoimmune disease that
manifests a wide range of organ involvement. Traditionally, the diagnosis and management …

Objectives∼ 30% of patients with SLE develop LN. Presence and/or severity of LN are
currently assessed by renal biopsy, but biomarkers in serum or urine samples may provide …

Is systemic lupus erythematosus (SLE) is occurring more frequently now than in decades
past? Despite improvements in the identification of patients with SLE, the development of …

Objective To evaluate the frequency of cell‐bound complement activation products (CB‐
CAP s) as a marker of complement activation in patients with suspected systemic lupus …

Testing for the presence of antinuclear antibodies (ANAs) is a key step in the diagnosis of
systemic lupus erythematosus (SLE) and other systemic autoimmune rheumatic diseases …

Background Approximately 30% of patients with the systemic autoimmune/inflammatory
disorder systemic lupus erythematosus (SLE) develop lupus nephritis (LN) that affects …

Autoantibodies (AA) and antinuclear antibodies (ANA) serve as key diagnostic and
classification criteria for systemic lupus erythematosus (SLE). More than 200 different AA …