HIV infection: epidemiology, pathogenesis, treatment, and prevention

G Maartens, C Celum, SR Lewin - The Lancet, 2014 - thelancet.com
HIV prevalence is increasing worldwide because people on antiretroviral therapy are living
longer, although new infections decreased from 3· 3 million in 2002, to 2· 3 million in 2012 …

The role of innate immunity in natural elite controllers of HIV-1 infection

Y Shi, J Su, R Chen, W Wei, Z Yuan, X Chen… - Frontiers in …, 2022 - frontiersin.org
The natural process of human immunodeficiency virus type 1 (HIV-1) infection is
characterized by high viral load, immune cell exhaustion, and immunodeficiency, which …

Effect of probiotics (Saccharomyces boulardii) on microbial translocation and inflammation in HIV-treated patients: a double-blind, randomized, placebo-controlled trial

J Villar-García, JJ Hernández… - JAIDS Journal of …, 2015 - journals.lww.com
Background: Microbial translocation has been associated with an increase in immune
activation and inflammation in HIV infection despite effective highly active antiretroviral …

Extracellular vesicles and chronic inflammation during HIV infection

PS Pérez, MA Romaniuk, GA Duette… - Journal of …, 2019 - Taylor & Francis
Inflammation is a hallmark of HIV infection. Among the multiple stimuli that can induce
inflammation in untreated infection, ongoing viral replication is a primary driver. After …

Malignancies in HIV-infected and AIDS patients

Y Ji, H Lu - Infectious Agents Associated Cancers: Epidemiology …, 2017 - Springer
Currently, HIV infection and AIDS are still one of the most important epidemic diseases
around the world. As early in the initial stage of HIV epidemic, the high incidence of ADCs …

Inflammatory co-morbidities in HIV+ individuals: learning lessons from healthy ageing

AC Hearps, GE Martin, R Rajasuriar… - Current HIV/AIDS …, 2014 - Springer
Increased life expectancy due to improved efficacy of cART has uncovered an increased risk
of age-related morbidities in HIV+ individuals and catalyzed significant research into …

Cancer prevention in HIV-infected populations

PH Goncalves, JM Montezuma-Rusca, R Yarchoan… - Seminars in …, 2016 - Elsevier
People living with human immunodeficiency virus (HIV) are living longer since the advent of
effective combined antiretroviral therapy (cART). While cART substantially decreases the …

Epstein-Barr virus–and Kaposi sarcoma-associated herpesvirus–related malignancies in the setting of human immunodeficiency virus infection

MR Pinzone, M Berretta, B Cacopardo, G Nunnari - Seminars in oncology, 2015 - Elsevier
The human gammaherpesvirus family includes Epstein-Barr virus (EBV) and human
herpesvirus (HHV)-8, also known as Kaposi sarcoma–associated herpesvirus (KSHV). In …

Serum levels of cytokines and biomarkers for inflammation and immune activation, and HIV-associated non-Hodgkin B-cell lymphoma risk

E Vendrame, SK Hussain, EC Breen… - … Biomarkers & Prevention, 2014 - AACR
Background: HIV infection is associated with a marked increase in risk for non-Hodgkin
lymphoma (AIDS-NHL). However, the mechanisms that promote the development of AIDS …

Carbohydrate supplementation retains intestinal barrier and ameliorates bacterial translocation in an antibiotic-induced mouse model

Y Zhang, WAS Aldamarany, L Deng, G Zhong - Food & Function, 2023 - pubs.rsc.org
Bacterial translocation (BT), with antibiotic use as an inducer, is associated with increased
risk of developing multiple inflammatory disorders, and is closely associated with intestinal …