Factors affecting treatment selection and overall survival for first-line EGFR-tyrosine kinase inhibitor therapy in non-small-cell lung cancer

YJ Kim, M Oremus, HH Chen… - Journal of …, 2020 - becarispublishing.com
Aim: To investigate the factors associated with treatment selection and overall survival for
first-line EGFR-tyrosine kinase inhibitors (EGFR-TKIs) therapy among patients with non …

Molecular docking, QSAR, and simulation analyses of EGFR-targeting phytochemicals in non-small cell lung cancer

MEK Talukder, MF Atif, NH Siddiquee… - Journal of Molecular …, 2024 - Elsevier
Non-small cell lung carcinoma (NSCLC) is one of the prominent categories of cancer
worldwide. It is primarily linked to mutations in the EGFR kinase domain, leading to being …

Tissue or liquid rebiopsy? A prospective study for simultaneous tissue and liquid NGS after first‐line EGFR inhibitor resistance in lung cancer

YT Lin, CC Ho, WH Hsu, WY Liao, CY Yang… - Cancer …, 2024 - Wiley Online Library
Abstract Introduction According to current International Association for the Study of Lung
Cancer guideline, physicians may first use plasma cell‐free DNA (cfDNA) methods to …

Sequential treatment in advanced epidermal growth factor receptor-mutated lung adenocarcinoma patients receiving first-line bevacizumab combined with 1st/2nd …

PC Hsu, CY Huang, YC Lin, SH Lee, LC Chiu… - Frontiers in …, 2023 - frontiersin.org
Introduction The clinical outcomes of sequential treatment of advanced epidermal growth
factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) patients with first-line …

Biomarkers involved in the proliferation of the odontogenic keratocyst, glandular odontogenic cyst and botryoid odontogenic cyst

JF Júnior, GM de França, CC da Silva Barros… - Oral and Maxillofacial …, 2022 - Springer
Introduction Odontogenic cysts are a heterogeneous group of lesions with varied clinical
behavior. Objective To analyze the expression of the epidermal growth factor receptor …

First‐line treatment with irreversible tyrosine kinase inhibitors associated with longer OS in EGFR mutation‐positive non‐small cell lung cancer

PL Su, CW Chen, YL Wu, CC Lin, WC Su - Thoracic Cancer, 2021 - Wiley Online Library
Background Few studies have compared the efficacy of the irreversible epidermal growth
factor receptor tyrosine kinase inhibitor (EGFR‐TKI), afatinib, with that of reversible EGFR …

Differential prognostic value of tumor and plasma T790M mutations in EGFR TKI-treated advanced NSCLC

PH Tung, TH Chiu, ACC Huang, JS Ju… - Therapeutic …, 2024 - journals.sagepub.com
Background: Substitution of methionine for threonine at codon 790 (T790M) of epidermal
growth factor receptor (EGFR) represents the major mechanism of resistance to EGFR …

[HTML][HTML] Review of epidermal growth factor receptor-tyrosine kinase inhibitors administration to non-small-cell lung cancer patients undergoing hemodialysis

CC Lan, PC Hsieh, CY Huang, MC Yang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Non-small-cell lung cancer (NSCLC) causes significant mortality worldwide. Patients with
chronic renal failure have an increased risk of developing lung cancer. NSCLC Patients with …

Integration of genomic profiling and organoid development in precision oncology

H Yoon, S Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Precision oncology involves an innovative personalized treatment strategy for each cancer
patient that provides strategies and options for cancer treatment. Currently, personalized …

A Phase IIIb Open-Label, Single-Arm Study of Afatinib in EGFR TKI-Naïve Patients with EGFRm+ NSCLC: Final Analysis, with a Focus on Patients Enrolled at Sites in …

HY Tu, J Feng, M Shi, J Zhao, Y Wang, J Chang… - Targeted Oncology, 2022 - Springer
Background Afatinib has been shown as a suitable option for the treatment of epidermal
growth factor receptor mutation-positive (EGFR m+) non-small-cell lung cancer (NSCLC) in …