Epidemiological aspects and world distribution of HTLV-1 infection

A Gessain, O Cassar - Frontiers in microbiology, 2012 - frontiersin.org
The human T-cell leukemia virus type 1 (HTLV-1), identified as the first human oncogenic
retrovirus 30 years ago, is not an ubiquitous virus. HTLV-1 is present throughout the world …

Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1–infected T cells

T Watanabe - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …

Blood transfusion safety in sub‐Saharan Africa: a literature review of changes and challenges in the 21st century

A Weimer, CT Tagny, JB Tapko, C Gouws… - …, 2019 - Wiley Online Library
BACKGROUND Access to a safe, adequate blood supply has proven challenging in sub‐
Saharan Africa, where systemic deficiencies spanning policy, collections, testing, and …

Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein

E Jaworski, A Narayanan, R Van Duyne… - Journal of Biological …, 2014 - ASBMB
Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia
and HTLV-1-associated myelopathy/tropical spastic paraparesis. The HTLV-1 transactivator …

Prevalence of human T-lymphotropic virus type 1 and 2 (HTLV-1/-2) infection in pregnant women in Brazil: a systematic review and meta-analysis

BA Vieira, AB Bidinotto, WJ Dartora, LG Pedrotti… - Scientific reports, 2021 - nature.com
Human T-lymphotropic virus type 1 (HTLV-1) infection may cause serious disease, while
pathogenicity of HTLV-2 is less certain. There are no screening or surveillance programs for …

Natural selection signatures in the Hondo and Ryukyu Japanese subpopulations

X Liu, M Matsunami, M Horikoshi, S Ito… - Molecular Biology …, 2023 - academic.oup.com
Natural selection signatures across Japanese subpopulations are under-explored. Here we
conducted genome-wide selection scans with 622,926 single nucleotide polymorphisms for …

CAR-iNKT cells targeting clonal TCRVβ chains as a precise strategy to treat T cell lymphoma

AG Rowan, K Ponnusamy, H Ren, GP Taylor… - Frontiers in …, 2023 - frontiersin.org
Introduction Most T cell receptor (TCR) Vβ chain-expressing T cell lymphomas (TCL)
including those caused by Human T cell leukaemia virus type-1 (HTLV-1) have poor …

Updates on HTLV-1 uveitis

K Kamoi, T Watanabe, K Uchimaru, A Okayama, S Kato… - Viruses, 2022 - mdpi.com
HTLV-1 uveitis (HU) is the third clinical entity to be designated as an HTLV-1-associated
disease. Although HU is considered to be the second-most frequent HTLV-1-associated …

Advances in preventive vaccine development against HTLV-1 infection: A systematic review of the last 35 years

CS Santana, FO Andrade, GCS da Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction The Human T-lymphotropic virus type 1 (HTLV-1) was the first described human
retrovirus. It is currently estimated that around 5 to 10 million people worldwide are infected …

Early‐life exposures to infectious agents and later cancer development

V Vedham, M Verma, S Mahabir - Cancer medicine, 2015 - Wiley Online Library
There is a growing understanding that several infectious agents are acquired in early life
and this is the reason why available vaccines target the new born, infants, and adolescents …