[HTML][HTML] Applying logistic LASSO regression for the diagnosis of atypical Crohn's disease

Y Li, F Lu, Y Yin - Scientific Reports, 2022 - nature.com
In countries with a high incidence of tuberculosis, the typical clinical features of Crohn's
disease (CD) may be covered up after tuberculosis infection, and the identification of …

[HTML][HTML] Six macrophage-associated genes in synovium constitute a novel diagnostic signature for osteoarthritis

Y Liu, T Lu, Z Liu, W Ning, S Li, Y Chen, X Ge… - Frontiers in …, 2022 - frontiersin.org
Background Synovial macrophages play important roles in the formation and progression of
osteoarthritis (OA). This study aimed to explore the biological and clinical significance of …

[HTML][HTML] Identification of cross-talk pathways and ferroptosis-related genes in periodontitis and type 2 diabetes mellitus by bioinformatics analysis and experimental …

S Pan, B Hu, J Sun, Z Yang, W Yu, Z He, X Gao… - Frontiers in …, 2022 - frontiersin.org
Purpose There is a bidirectional relationship between periodontitis and type 2 diabetes
mellitus (T2DM). The aim of this study was to further explore the pathogenesis of this …

[HTML][HTML] Bioinformatic analysis of underlying mechanisms of Kawasaki disease via Weighted Gene Correlation Network Analysis (WGCNA) and the Least Absolute …

Y Xie, H Shi, B Han - BMC pediatrics, 2023 - Springer
Background Kawasaki disease (KD) is a febrile systemic vasculitis involvingchildren
younger than five years old. However, the specific biomarkers and precise mechanisms of …

[HTML][HTML] Immunological risk factors for sepsis-associated delirium and mortality in ICU patients

W Lei, Z Ren, J Su, X Zheng, L Gao, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Background A major challenge in intervention of critical patients, especially sepsis-
associated delirium (SAD) intervention, is the lack of predictive risk factors. As sepsis and …

[HTML][HTML] Screening of potential key ferroptosis-related genes in sepsis

S Cui, K Niu, Y Xie, S Li, W Zhu, L Yu, H Tan - PeerJ, 2022 - peerj.com
Background Sepsis leads to multiple organ dysfunction caused by a dysregulated host
response to infection with a high incidence and mortality. The effect of ferroptosis on the …

[HTML][HTML] Transcriptome-based dissection of intracranial aneurysms unveils an “Immuno-Thermal” microenvironment and defines a pathological feature-derived gene …

T Lu, Z Liu, D Guo, C Ma, L Duan, Y He, R Jia… - Frontiers in …, 2022 - frontiersin.org
Immune inflammation plays an essential role in the formation and rupture of intracranial
aneurysm (IA). However, the current limited knowledge of alterations in the immune …

[HTML][HTML] Identification of new co-diagnostic genes for sepsis and metabolic syndrome using single-cell data analysis and machine learning algorithms

L Tao, Y Zhu, J Liu - Frontiers in Genetics, 2023 - frontiersin.org
Sepsis, a serious inflammatory response that can be fatal, has a poorly understood
pathophysiology. The Metabolic syndrome (MetS), however, is associated with many …

[HTML][HTML] Bioinformatics analysis of gene expression profiles for diagnosing sepsis and risk prediction in patients with sepsis

H Choi, JY Lee, H Yoo, K Jeon - International Journal of Molecular …, 2023 - mdpi.com
Although early recognition of sepsis is essential for timely treatment and can improve sepsis
outcomes, no marker has demonstrated sufficient discriminatory power to diagnose sepsis …

[HTML][HTML] Classification of subtypes and identification of dysregulated genes in sepsis

R Tong, X Ding, F Liu, H Li, H Liu, H Song… - Frontiers in Cellular …, 2023 - frontiersin.org
Background Sepsis is a clinical syndrome with high mortality. Subtype identification in
sepsis is meaningful for improving the diagnosis and treatment of patients. The purpose of …