Despite enormous advances, cardiovascular disorders are still a major threat to global
health and are responsible for one-third of deaths worldwide. Research for new therapeutics …

Considering cancer not only as malignant cells on their own but as a complex disease in
which tumor cells interact and communicate with their microenvironment has motivated the …

Schizophrenia (SCZ) is a complex neurodevelopmental disorder characterized by the
manifestation of psychiatric symptoms in early adulthood. While many research avenues into …

Diffuse high-grade gliomas contain some of the most dangerous human cancers that lack
curative treatment options. The recent molecular stratification of gliomas by the World Health …

Although significant improvements have been made in the treatment of pancreatic cancer, its
prognosis remains poor with an overall 5-year survival rate of less than 10%. New …

COVID-19 emerged in September 2020 as a disease caused by the virus SARS-CoV-2. The
disease presented as pneumonia at first but later was shown to cause multisystem infections …

Here we describe a novel neuro-mesodermal assembloid model that recapitulates aspects
of peripheral nervous system (PNS) development such as neural crest cell (NCC) induction …

Blood vessels constitute a closed pipe system distributed throughout the body, transporting
blood from the heart to other organs and delivering metabolic waste products back to the …

Organoids, self-organizing three-dimensional (3D) structures derived from stem cells, offer
unique advantages for studying organ development, modeling diseases, and screening …

Vascular pathologies are prevalent in a broad spectrum of diseases, necessitating a deeper
understanding of vascular biology, particularly in overcoming the oxygen and nutrient …