Despite significant progress, metastatic urothelial cancer remains an incurable condition
with a limited life expectancy. Platinum-based chemotherapy is still the mainstay of treatment …

Oligoprogressive disease is a relatively new clinical concept describing progression at only
a few sites of metastasis in patients with otherwise controlled widespread disease. In the era …

Adenoid cystic carcinoma (ACC) is a rare tumor, usually arising in the salivary gland,
accounting for 1% of all head and neck cancers. ACC may have a long-term poor prognosis …

The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Background and purpose Single-fraction stereotactic ablative radiotherapy (SABR) is an
effective treatment for early-stage lung cancer, but concerns remain about the accurate …

Photodynamic therapy (PDT) has been under development for at least 40 years. Multiple
studies have demonstrated significant anti-tumor efficacy with limited toxicity concerns. PDT …

Background Stereotactic ablative body radiotherapy (SABR) is an emerging noninvasive
approach for the treatment of oligometastases. Limited prospective evidence is available in …

Purpose The percentage of patients with metastatic non-small cell lung cancer (NSCLC) and
melanoma who benefit from anti–programmed cell death protein 1 (anti-PD-1) is low owing …

Background Available therapies for castrate-resistant prostate cancer (CRPC) confer
minimal survival advantage; thus, there is interest in metastasis-directed therapy (MDT) for …

During the past century, from the advent of preclinical modeling to the establishment of
clinical trials, the hypothesis that host defenses regulate tumor growth (posited and refined …