Adenosine receptors (ARs) function in the body's response to conditions of pathology and
stress associated with a functional imbalance, such as in the supply and demand of …

Adenosine is involved in a range of physiological and pathological effects through
membrane-bound receptors linked to G proteins. There are four subtypes of adenosine …

G protein-coupled receptors (GPCRs) remain a major domain of pharmaceutical discovery.
The identification of GPCR lead compounds and their optimization are now structure-based …

Adenosine is a purine nucleoside, responsible for the regulation of a wide range of
physiological and pathophysiological conditions by binding with four G-protein-coupled …

The sinoatrial node (SAN) is the primary pacemaker in canine and human hearts. The SAN
in both species has a unique three-dimensional heterogeneous structure characterized by …

Adenosine can be released from the heart and may stimulate four different cardiac
adenosine receptors. A receptor subtype that couples to the generation of cyclic adenosine …

The traditional Chinese medicine Poria cum Radix Pini (PRP) is a fungal medicinal material
that has been proven to play an important role in the treatment of arrhythmia. However, the …

Infertility rates for both females and males have increased continuously in recent years.
Currently, effective treatments for male infertility with defined mechanisms or targets are still …

One of the four G protein-coupled receptors for adenosine, the A 1 adenosine receptors (A 1
AR), is widely distributed in the body and modulates numerous normal and pathological …

Laboratory experiments were carried out to identify the chemical composition of Cordyceps
militaris and reveal the first evidence of their Alzheimer-related potential. Liquid …