Sjögren syndrome (SjS) is a systemic autoimmune disease that primarily affects the exocrine
glands (mainly the salivary and lacrimal glands) and results in the severe dryness of …

In primary Sjögren syndrome (pSS), chronic inflammation of exocrine glands results in tissue
destruction and sicca symptoms, primarily of the mouth and eyes. Fatigue, arthralgia and …

Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of
B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …

In 9–20% of cases, Sjögren's syndrome is associated with various respiratory symptoms.
The most typical manifestations are chronic interstitial lung disease (ILD) and …

Objectives Increasing evidence suggests an epigenetic contribution to the pathogenesis of
autoimmune diseases, including primary Sjögren's Syndrome (pSS). The aim of this study …

DNA methylation is a dynamic epigenetic modification with a prominent role in determining
mammalian cell development, lineage identity, and transcriptional regulation. Primarily …

Primary Sjögren's syndrome (pSS) is a complex and heterogeneous disorder characterised
by a wide spectrum of glandular and extra-glandular features. Novel insights into disease …

Primary Sjögren's syndrome (pSS) is considered to be a multifactorial disease, where
underlying genetic predisposition, epigenetic mechanisms and environmental factors …

Background Psoriasis is an autoimmune/inflammatory disorder primarily affecting the skin.
Chronic joint inflammation triggers the diagnosis of psoriatic arthritis (PsA) in approximately …

Objective MicroRNAs (miRNAs) play an important role in the pathogenesis of autoimmune
diseases such as primary Sjögren's syndrome (pSS). This study is the first to investigate …