What is known and objective The off‐label use of medicines is widespread in several
diseases. This type of prescribing practice is particularly more acute in oncology. However …

Background In the past two decades, many legislative and regulatory initiatives were taken
globally to improve drug use in children. However, children are still found to be prescribed …

BACKGROUND: Off-label drug use in children is common and potentially harmful. In most
previous off-label use research, authors studied hospitalized children, specific drug classes …

Background: Given the growing use of off-label in pediatric practice, there is a growing
interest on pharmacovigilance programs monitoring the occurrence of adverse drug …

Extemporaneous preparations are still widely prescribed for pediatric patients with special
treatments of certain doses and/or combinations of drugs. Several problems related to …

In 2019 five clinicians working at the Gender Identity Development Service (GIDS) at the
Tavistock and Portman NHS Foundation Trust in London in the United Kingdom (UK) …

Despite advances in regulations and initiatives to increase pediatric medicine development,
there is still an unmet need for age-appropriate medicines for children. The availability of …

Introduction Off-label (OL) and unlicensed (UL) drug use is widely developed in the pediatric
population according to previous reviews published in the early 2010s. The present study is …

Off-label prescribing is widespread among pediatricians, and it is unlikely that this trend will
soon be bound by a uniform legal framework. This is necessitated by the fact that there are …

Highlights•Patient acceptability is crucial for pharmaceutical products.•We review
acceptability assessment methods in paediatric and geriatric patients.•The published …