Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

The aging and elderly population are particularly susceptible to cardiovascular disease. Age
is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are …

The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

Osteoporosis is called the 'silent disease'because, although it does not give significant
symptoms when it is not complicated, can cause fragility fractures, with serious …

Although intrinsic mechanisms that regulate arterial blood pressure (BP) are similar in men
and women, marked variations exist at the molecular, cellular and tissue levels. These …

Diseases of the cardiovascular system are the leading cause of morbidity and mortality in
men and women in developed countries, and cardiovascular disease (CVD) is becoming …

Objective: Anxiety disorders are common and often disabling. The goal of this study was to
examine the genetic architecture of anxiety disorders and anxiety symptoms, which are also …

Over the last two decades, it has become evident that estrogens preserve the integrity of
energy homeostasis at central and peripheral levels. Estrogen deficiency, such as that …

Bone is a multi-skilled tissue, protecting major organs, regulating calcium phosphate
balance and producing hormones. Its development during childhood determines height and …

Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …