Pleasurable and problematic receptive anal intercourse and diseases of the colon, rectum and anus

DR Dickstein, CR Edwards, CR Rowan… - Nature Reviews …, 2024 - nature.com
The ability to experience pleasurable sexual activity is important for human health.
Receptive anal intercourse (RAI) is a common, though frequently stigmatized, pleasurable …

[HTML][HTML] Total neoadjuvant therapy in rectal cancer: the evidence and expectations

B Ludmila, N Alena, S Jaromir, L Radka - Critical Reviews in Oncology …, 2023 - Elsevier
Current management of locally advanced rectal cancer achieves high cure rates, distant
metastatic spread being the main cause of patients' death. Total neoadjuvant therapy (TNT) …

[HTML][HTML] Total Neoadjuvant Treatment for Locally Advanced Rectal Cancer Patients: Where Do We Stand?

V Daprà, M Airoldi, M Bartolini, R Fazio… - International Journal of …, 2023 - mdpi.com
The therapeutic landscape in locally advanced rectal cancer (LARC) has undergone a
significant paradigm shift in recent years with the rising adoption of total neoadjuvant …

[HTML][HTML] Deciphering treatment resistance in metastatic colorectal cancer: roles of drug transports, EGFR mutations, and HGF/c-MET signaling

N Albadari, Y Xie, W Li - Frontiers in Pharmacology, 2024 - frontiersin.org
In 2023, colorectal cancer (CRC) is the third most diagnosed malignancy and the third
leading cause of cancer death worldwide. At the time of the initial visit, 20% of patients …

[HTML][HTML] Radiotherapy in the preoperative neoadjuvant treatment of locally advanced rectal cancer

Z Yu, Y Hao, Y Huang, L Ling, X Hu, S Qiao - Frontiers in Oncology, 2023 - frontiersin.org
Radiotherapy and chemotherapy are effective treatments for patients with locally advanced
rectal cancer (LARC) and can significantly improve the likelihood of R0 resection …

Neoadjuvant chemotherapy with/without radiotherapy for locally advanced rectal cancer: a nationwide retrospective cohort study

T Ke, S Chang, Y Liao, CH Lin, WTL Chen… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: The role of neoadjuvant radiotherapy in the management of patients with
locally advanced rectal cancer (LARC) who have undergone neoadjuvant systemic therapy …

[HTML][HTML] Unlocking digitally enabled research in oncology: the time is now

MA Franzoi, E Gillanders, I Vaz-Luis - ESMO open, 2023 - esmoopen.com
Extraordinary advances in cancer screening, therapeutics, and supportive care have
contributed to substantial progress in survival rates among patients with cancer over the last …

Patient-reported outcomes in Chinese patients with locally advanced or recurrent colorectal cancer after pelvic exenteration

X Lin, Z Haiyang - Annals of Surgical Oncology, 2024 - Springer
Background Pelvic exenteration (PE) is often the only curative treatment option for selected
locally advanced and locally recurrent colorectal cancer associated with significant …

[HTML][HTML] Patient-Reported Sexual Function, Bladder Function and Quality of Life for Patients with Low Rectal Cancers with or without a Permanent Ostomy

MK Rooney, M Pasli, GJ Chang, P Das, EJ Koay… - Cancers, 2023 - mdpi.com
Simple Summary This survey study investigates long-term patient-reported quality of life for
individuals with low-lying rectal cancers, particularly focusing on the potential impact that …

Evolution of therapy for locally advanced rectal cancer

NJ Altomare, MF Mulcahy - Journal of surgical oncology, 2024 - Wiley Online Library
Rectal cancer is a prevalent disease worldwide. The standard treatment of locally advanced
rectal cancer (LARC) is preoperative chemoradiotherapy followed by surgery and adjuvant …