[HTML][HTML] Antimicrobial peptides: classification, design, application and research progress in multiple fields

Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …

Antimicrobial peptides (AMPs): A promising class of antimicrobial compounds

M Erdem Büyükkiraz, Z Kesmen - Journal of Applied …, 2022 - academic.oup.com
Antimicrobial peptides (AMPs) are compounds, which have inhibitory activity against
microorganisms. In the last decades, AMPs have become powerful alternative agents that …

Staphylococcal biofilm development: structure, regulation, and treatment strategies

K Schilcher, AR Horswill - Microbiology and Molecular Biology …, 2020 - Am Soc Microbiol
In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Antibiofilm activity of host defence peptides: Complexity provides opportunities

REW Hancock, MA Alford, EF Haney - Nature Reviews Microbiology, 2021 - nature.com
Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

[HTML][HTML] Natural anti-biofilm agents: strategies to control biofilm-forming pathogens

R Mishra, AK Panda, S De Mandal, M Shakeel… - Frontiers in …, 2020 - frontiersin.org
Pathogenic microorganisms and their chronic pathogenicity are significant concerns in
biomedical research. Biofilm-linked persistent infections are not easy to treat due to resident …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

Targeting microbial biofilms: current and prospective therapeutic strategies

H Koo, RN Allan, RP Howlin, P Stoodley… - Nature Reviews …, 2017 - nature.com
Biofilm formation is a key virulence factor for a wide range of microorganisms that cause
chronic infections. The multifactorial nature of biofilm development and drug tolerance …

[HTML][HTML] Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds

A Pfalzgraff, K Brandenburg, G Weindl - Frontiers in pharmacology, 2018 - frontiersin.org
Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …

[HTML][HTML] Microbiological aspects of root canal infections and disinfection strategies: an update review on the current knowledge and challenges

J Wong, D Manoil, P Näsman, GN Belibasakis… - Frontiers in Oral …, 2021 - frontiersin.org
The oral cavity is the habitat of several hundreds of microbial taxa that have evolved to
coexist in multispecies communities in this unique ecosystem. By contrast, the internal tissue …

Peptidomimetic polyurethanes inhibit bacterial biofilm formation and disrupt surface established biofilms

A Vishwakarma, F Dang, A Ferrell… - Journal of the …, 2021 - ACS Publications
Over 80% of all chronic bacterial infections in humans are associated with biofilms, which
are surface-associated bacterial communities encased within a secreted exopolysaccharide …