Therapy to obese type 2 diabetes mellitus: how far will we go down the wrong road?

X Heng, X Li, L Li, L Yang, Z Wang, S Huang - Chinese Journal of …, 2020 - Springer
Traditional glucose-lowering chemical agents, including various types of insulin and insulin
secretagogues, insulin sensitizers, gliptins, etc., are based on diabetic pathogenesis of …

Dan-gua Fang (丹瓜方) improves glycolipid metabolic disorders by promoting hepatic adenosine 5′-monophosphate activated protein kinase expression in diabetic …

Y Lan, S Huang, X Heng, L Chen, P Li, J Wu… - Chinese journal of …, 2015 - Springer
Objective To investigate the effect of Dan-gua Fang (丹瓜方) on adenosine 5′-
monophosphate (AMP) activated protein kinase (AMPK) α expression in liver and …

Toxicity features of high glucose on endothelial cell cycle and protection by Dan Gua-Fang (丹瓜方) in ECV-304 in high glucose medium

X Heng, K Chen, Z Hong, W He, K Chu, J Lin… - Chinese journal of …, 2013 - Springer
Objective: To study the toxicity features of high glucose on the endothelial cell cycle and the
influence of Dan Gua-Fang (丹瓜方), a Chinese herbal compound prescription, on the …

[PDF][PDF] 丹栝方干预糖尿病动脉粥样硬化大鼠糖脂代谢及氧化应激研究

衡先培, 黄苏萍, 程心玲, 蓝元隆, 杨柳清, 潘旭东… - 2013 - researchgate.net
衡先培1 黄苏萍2 程心玲1 蓝元隆2 杨柳清1 潘旭东1 陈玲3 林久茂2 李鹏辉4 吴静4 林妙娴4
陈敏灵1 谢瑜1 郭芳1 丁宗平4 雷缨5 摘要目的探讨丹栝方对糖尿病动脉粥样硬化大鼠糖脂代谢 …

[HTML][HTML] Mechanisms of Dangua Fang (丹瓜方) in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics

H Xianpei, W Zhita, LI Liang, Y Liuqing… - Journal of Traditional …, 2024 - ncbi.nlm.nih.gov
OBJECTIVE: To explore the mechanism of Dangua Fang (丹瓜方, DGR) in multi-target and
multi-method regulation of glycolipid metabolism based on phosphoproteomics. METHODS …

丹瓜方对Apo E-/-糖尿病模型小鼠糖脂代谢及血管细胞黏附分子-1 及mRNA 表达水平的影响

衡先培, 李亮, 黄苏萍, 陈燕 - 中国中西医结合杂志, 2014 - cjim.cn
目的研究丹瓜方对载脂蛋白E 基因敲除(ApoE-/-) 小鼠复合糖尿病模型糖脂代谢指标,
血管细胞黏附分子1 (vascular cell adhesion molecule 1, VCAM 1) 及其mRNA …

Tanshinone II a protects against lipopolysaccharides-induced endothelial cell injury via Rho/Rho kinase pathway

W Li, W Sun, C Yang, H Hu, Y Jiang - Chinese journal of integrative …, 2014 - Springer
Objective To test whether tanshinone II A (Tan II A), a highly valued herb derivative to treat
vascular diseases in Chinese medicine, could protect endothelial cells from bacterial …

[PDF][PDF] 基于代谢病肝病传脾探索早期干预2 型糖尿病的新思路

衡先培, 杨柳清, 李亮 - 中国中西医结合杂志, 2015 - cjim.cn
摘要能量过剩已经成为日益严峻的危害我国人群健康的主因" 过剩的能量以甘油三酯的形式主要
在肝脏# 也可在胰腺等器官异位沉积$ 产生慢性氧化和硝基化应激% J4L& 及脂毒性 …

Effects of bleomycin A5 on caspase-3, P53, bcl-2 expression and telomerase activity in vascular endothelial cells

YD Huang, P Li, X Tong, Y He, Y Zhuo… - Indian Journal of …, 2015 - journals.lww.com
Objective: The aim of this study was to investigate the molecular mechanism of bleomycin
A5 in inducing the apoptosis of human umbilical vein endothelial cells (ECV304). Materials …

Paradox of using intensive lowering of blood glucose in diabetics and strategies to overcome it and decrease cardiovascular risks

X Heng, L Yang, M Chen, L Li, S Huang… - Chinese journal of …, 2015 - Springer
Hyperglycemia significantly increases the risk of cardiovascular disease (CVD) in diabetics.
However, it has been shown by a series of large scale international studies that intensive …