The landscape of the methodology in drug repurposing using human genomic data: a systematic review

L Wang, Y Lu, D Li, Y Zhou, L Yu… - Briefings in …, 2024 - academic.oup.com
The process of drug development is expensive and time-consuming. In contrast, drug
repurposing can be introduced to clinical practice more quickly and at a reduced cost. Over …

[HTML][HTML] Progress in the treatment of lung adenocarcinoma by integrated traditional Chinese and Western medicine

H Jiang, L Bu - Frontiers in Medicine, 2024 - frontiersin.org
Non-small cell lung cancer (NSCLC) overwhelmingly represents the predominant
histological subtype of lung cancer, with lung adenocarcinoma emerging as the most …

Exploring the interaction of biologically active compounds with DNA through the application of the SwitchSense technique, UV–Vis spectroscopy, and computational …

A Ciesielska, J Brzeski, D Zarzeczańska… - … Acta Part A: Molecular …, 2024 - Elsevier
DNA is a key target for anticancer and antimicrobial drugs. Assessing the bioactivity of
compounds involves in silico and instrumental studies to determine their affinity for …

Multitype perception method for drug-target interaction prediction

H Wang, R Liu, B Wang, Y Hong… - IEEE/ACM Transactions …, 2023 - ieeexplore.ieee.org
With the growing popularity of artificial intelligence in drug discovery, many deep-learning
technologies have been used to automatically predict unknown drug-target interactions …

A weighted integration method based on graph representation learning for drug repositioning

H Lian, P Ding, C Yu, X Zhang, G Liu, B Yu - Applied Soft Computing, 2024 - Elsevier
The time-consuming and expensive nature of traditional drug discovery necessitates a cost-
effective approach to facilitate disease treatment. Drug repositioning, discovering innovative …

The Human Pathology Atlas for deciphering the prognostic features of human cancers

M Yuan, C Zhang, K von Feilitzen, M Zwahlen, M Shi… - 2024 - researchsquare.com
Cancer is one of the leading causes of mortality worldwide, highlighting the urgent need for
a deeper molecular understanding of the disease's heterogeneity and the development of …

Exploring the Interaction of Biologically Active Compounds with DNA Using the Switchsense Technique, Uv-Vis Spectroscopy, and Computational Methods

A Ciesielska, J Brzeski, D Zarzeczanska… - Uv-Vis Spectroscopy … - papers.ssrn.com
Deoxynucleic acid (DNA) is one of the molecular targets against which anticancer and
antimicrobial drugs act. An important element in the assessment of the biological activity of …