Graft-versus-tumor effect of post-transplant cyclophosphamide-based allogeneic hematopoietic cell transplantation

H Nakamae - Frontiers in Immunology, 2024 - frontiersin.org
Post-transplant cyclophosphamide (PTCy) is becoming the standard prophylaxis for graft-
versus-host disease (GVHD) in HLA-haploidentical allogeneic hematopoietic cell …

[HTML][HTML] Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury

JH Riedel, L Robben, HJ Paust, Y Zhao, N Asada… - JCI insight, 2023 - ncbi.nlm.nih.gov
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic
inflammatory diseases—for example, in different forms of crescentic glomerulonephritis …

[HTML][HTML] Mocravimod, a selective sphingosine-1-phosphate receptor modulator, in allogeneic hematopoietic stem cell transplantation for malignancy

S Dertschnig, P Gergely, J Finke, U Schanz… - … and Cellular Therapy, 2023 - Elsevier
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the sole curative
option for patients with acute myelogenous leukemia. Outcomes are limited by leukemia …

A prospective study of an HLA-haploidentical peripheral blood stem cell transplantation regimen based on modification of the dose of posttransplant …

H Nakamae, H Okamura, A Hirose, H Koh… - Cell …, 2022 - journals.sagepub.com
The optimal dose of posttransplant cyclophosphamide (PTCy) for use in patients undergoing
HLA-haploidentical hematopoietic cell transplantation with posttransplant …

Individualized rabbit anti‐thymocyte globulin dosing in adult haploidentical hematopoietic cell transplantation with high‐risk hematologic malignancy: Exposure …

M Teramoto, T Takahashi, K Matsumoto… - American Journal of …, 2024 - Wiley Online Library
Hematopoietic cell transplantation (HCT) for hematologic malignancies with non‐remission
disease and/or prior post‐transplant relapse have poor relapse‐free survival. We previously …

[HTML][HTML] Posttransplant cyclophosphamide contributes to the impairment of the graft-versus-leukemia effect and the amelioration of graft-versus-host disease with the …

Y Makuuchi, Y Nakashima, M Nishimoto, H Koh… - Experimental …, 2023 - Elsevier
Posttransplant cyclophosphamide (PTCy) is an effective prophylaxis for graft-versus-host
disease (GVHD) due to its suppression of donor-derived alloreactive T cells in allogeneic …

[HTML][HTML] Peritransplantation glucocorticoid haploidentical stem cell transplantation is a promising strategy for AML patients with high leukemic burden: comparison with …

K Kaida, K Ikegame, T Inoue, S Maruyama… - … and Cellular Therapy, 2023 - Elsevier
Using a murine haploidentical bone marrow transplantation (BMT) model, we recently
showed that peritransplantation administration of glucocorticoid (GC) redistributed donor T …

Pretransplantation predictors of survival in nonremission acute myeloid leukemia treated with haploidentical transplantation using steroid-based GVHD prophylaxis

M Teramoto, H Tamaki, K Kaida, M Samori… - Annals of …, 2024 - Springer
Haploidentical hematopoietic cell transplantation (HCT) using glucocorticoids for acute graft-
versus-host disease prophylaxis (GC-haplo) may become a curative treatment option for …

[PDF][PDF] Glucocorticoids target the CXCL9/10-CXCR3 axis and confer protection against immune-mediated kidney injury

JH Riedel, CF Krebs, U Panzer - Am Soc Clin Investig
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic
inflammatory diseases, for example, in different forms of crescentic glomerulonephritis …

[PDF][PDF] Transplantation and Cellular Therapy

S Dertschnig, P Gergely, J Finke, U Schanz, E Holler… - 2022 - priothera.com
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) remains the sole curative
option for patients with acute myelogenous leukemia. Outcomes are limited by leukemia …