Cell sheet engineering (CSE) has emerged as a novel strategy promising for cellular
therapies and scaffold-free tissue engineering. In contrast to conventional cell-based or …

Periodontitis is a worldwide chronic inflammatory disease, where surgical treatment still
shows an uncertain prognosis. To break through the dilemma of periodontal treatment, we …

The extracellular matrix (ECM) of the tissue organ exhibits a topography from the nano to
micrometer range, and the design of scaffolds has been inspired by the host environment …

Transmembrane transport of exogenous genes is widely investigated because of high
demand for gene therapy. Both gene carriers and cellular conditions can affect gene …

Within the heterogeneous tissue architecture, a comprehensive understanding of how cell
shapes regulate cytoskeletal mechanics by adjusting focal adhesions (FAs) signals to …

Articular cartilage tissue has limited self-repair capabilities, with damage frequently
progressing to irreversible degeneration. Engineered tissues constructed through …

A major challenge for the tissue engineering is the regulation of cell behavior using
topographical cues of the artificial biomaterials without biochemical stimuli. In this study …

Diabetic nephropathy (DN) is a substantial healthcare challenge as a complication of
diabetes, owing to the high risk of morbidity and mortality involved. Although significant …

Hypothesis Interfacial adhesion caused by intermolecular forces only occur between
surfaces at nano-scale contact (NSC), ie, 0.1–0.4 nm and can be evaluated using Forster …

Critical-size defects (CSDs) of the craniofacial bones cause aesthetic and functional
complications that seriously impact the quality of life. The transplantation of human dental …