[HTML][HTML] Vascular dysfunction in Alzheimer's disease: a prelude to the pathological process or a consequence of it?

K Govindpani, LG McNamara, NR Smith… - Journal of clinical …, 2019 - mdpi.com
Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

[HTML][HTML] Breast milk: A source of functional compounds with potential application in nutrition and therapy

C Sánchez, L Franco, P Regal, A Lamas, A Cepeda… - Nutrients, 2021 - mdpi.com
Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in
its different stages of growth up to six months after birth. In addition, breastfeeding benefits …

Lupus antibodies induce behavioral changes mediated by microglia and blocked by ACE inhibitors

J Nestor, Y Arinuma, TS Huerta, C Kowal… - Journal of Experimental …, 2018 - rupress.org
Cognitive impairment occurs in 40–90% of patients with systemic lupus erythematosus
(SLE), which is characterized by autoantibodies to nuclear antigens, especially DNA. We …

[HTML][HTML] Neuropsychiatric disorders in chronic kidney disease

AC Simoes e Silva, AS Miranda, NP Rocha… - Frontiers in …, 2019 - frontiersin.org
Neuropsychiatric conditions including depression, anxiety disorders, and cognitive
impairment are prevalent in patients with chronic kidney disease (CKD). These conditions …

[HTML][HTML] Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer's disease: Past, present and future

F Gouveia, A Camins, M Ettcheto, J Bicker… - Ageing Research …, 2022 - Elsevier
Alzheimer's disease (AD) is a well-known neurodegenerative disease characterized by the
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …

[HTML][HTML] The coming of age of the angiotensin hypothesis in Alzheimer's disease: progress toward disease prevention and treatment?

PG Kehoe - Journal of Alzheimer's Disease, 2018 - content.iospress.com
There is wide recognition of a complex association between midlife hypertension and
cardiovascular disease and later development of Alzheimer's disease (AD) and cognitive …

[HTML][HTML] Targeting renin–angiotensin system against Alzheimer's disease

AK Gebre, BM Altaye, TM Atey, KB Tuem… - Frontiers in …, 2018 - frontiersin.org
Renin Angiotensin System (RAS) is a hormonal system that regulates blood pressure and
fluid balance through a coordinated action of renal, cardiovascular, and central nervous …

[HTML][HTML] The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer's disease: the importance of blood …

M Ouk, CY Wu, JS Rabin, A Jackson… - Alzheimer's Research & …, 2021 - Springer
Background The antihypertensive angiotensin receptor blockers (ARBs) and angiotensin-
converting enzyme inhibitors (ACE-Is) have similar indications and mechanisms of action …

Hypertension and hyperhomocysteinemia as modifiable risk factors for Alzheimer's disease and dementia: New evidence, potential therapeutic strategies, and …

A Carey, S Fossati - Alzheimer's & Dementia, 2023 - Wiley Online Library
This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …

Cognitive dysfunction in SLE: an understudied clinical manifestation

M Mizrachi, E Anderson, KR Carroll, N Tehrani… - Journal of …, 2022 - Elsevier
Neuropsychiatric lupus (NPSLE) is a debilitating manifestation of SLE which occurs in a
majority of SLE patients and has a variety of clinical manifestations. In the central nervous …