Nanobiotechnology-based treatment strategies for malignant relapsed glioma

Q Qiu, X Ding, J Chen, S Chen, J Wang - Journal of Controlled Release, 2023 - Elsevier
Gliomas are the most aggressive and lethal tumors of the central nervous system, for which
few therapeutic options exist. Surgical resection is the primary treatment for most gliomas; …

Nanoparticle‐mediated STING activation for cancer immunotherapy

Y Li, X Li, J Yi, Y Cao, Z Qin, Z Zhong… - Advanced Healthcare …, 2023 - Wiley Online Library
As the first line of host defense against pathogenic infections, innate immunity plays a key
role in antitumor immunotherapy. The cyclic GMP‐AMP synthase (cGAS)‐stimulator of …

Nanoparticles hitchhike on monocytes for glioblastoma treatment after low-dose radiotherapy

J Kuang, ZY Rao, DW Zheng, D Kuang, QX Huang… - ACS …, 2023 - ACS Publications
Glioblastomas (GBMs) are aggressive primary brain tumors with fatal outcome. Traditional
chemo-radiotherapy has poor therapeutic effect and significant side effects, due to the drug …

In situ forming pH/ROS-responsive niche-like hydrogel for ultrasound-mediated multiple therapy in synergy with potentiating anti-tumor immunity

Z Dai, Q Zhang, X Li, Q Chen, J Chen, M Wang… - Materials Today, 2023 - Elsevier
Tumor immunosuppressive microenvironment (TIME) often causes suppression of anti-
tumor immunity and increases susceptibility to tumor recurrence and metastasis. Herein, a …

Homotypic membrane-enhanced blood–brain barrier crossing and glioblastoma targeting for precise surgical resection and photothermal therapy

H Zhang, S Guan, T Wei, T Wang, J Zhang… - Journal of the …, 2023 - ACS Publications
The crossing of blood–brain barrier (BBB) is essential for glioblastoma (GBM) therapy, and
homotypic targeting is an effective strategy to achieve BBB crossing. In this work, GBM …

Injectable smart stimuli-responsive hydrogels: pioneering advancements in biomedical applications

J Liu, C Du, W Huang, Y Lei - Biomaterials Science, 2024 - pubs.rsc.org
Hydrogels have established their significance as prominent biomaterials within the realm of
biomedical research. However, injectable hydrogels have garnered greater attention …

X‐ray excited luminescence materials for cancer diagnosis and theranostics

Q Ma, Y Cao, X Ge, Z Zhang, S Gao… - Laser & Photonics …, 2024 - Wiley Online Library
X‐rays are rays that penetrate the human tissue and are capable of penetrating water, air,
and oxygen in various biological tissues or tumors. In recent years, significant progress has …

Multimodal neuro-nanotechnology: Challenging the existing paradigm in glioblastoma therapy

S Kudruk, CM Forsyth, MZ Dion… - Proceedings of the …, 2024 - National Acad Sciences
Integrating multimodal neuro-and nanotechnology-enabled precision immunotherapies with
extant systemic immunotherapies may finally provide a significant breakthrough for …

Nanointegrative in situ reprogramming of Tumor-intrinsic lipid Droplet Biogenesis for Low-Dose Radiation-activated ferroptosis immunotherapy

Q Zhang, X Wang, Y Zhao, Z Cheng, D Fang, Y Liu… - ACS …, 2023 - ACS Publications
Low-dose radiotherapy (LDR) has shown significant implications for inflaming the
immunosuppressive tumor microenvironment (TME). Surprisingly, we identify that FABP …

Multiple therapeutic approaches of glioblastoma multiforme: From terminal to therapy

S Kumari, R Gupta, RK Ambasta, P Kumar - Biochimica et Biophysica Acta …, 2023 - Elsevier
Glioblastoma multiforme (GBM) is an aggressive brain cancer showing poor prognosis.
Currently, treatment methods of GBM are limited with adverse outcomes and low survival …