Thyroid nodules are quite common, and the determination of a nodule of concern is
complex, involving serum testing, radiology and, in some cases, pathological evaluation. For …

A widely discussed topic in the pathophysiology of thyroid nodules is the role of obesity, a
state that leads to increased systemic inflammatory markers. Leptin plays a vital role in …

Thyroid nodules are common and the prevalence varies between 4 and 7% by palpation
and 19–68% by high-resolution USG. Most thyroid nodules are benign, and the malignancy …

A growing incidence of differentiated thyroid cancer (DTC) has been reported in most
developed countries, corresponding mainly to incidentally discovered small papillary thyroid …

In recent years, machine learning (ML) has become a pivotal tool for predicting and
diagnosing thyroid disease. While many studies have explored the use of individual ML …

Context Telomerase reverse transcriptase (TERT) promoter-mutated thyroid cancers are
associated with a decreased rate of disease-free and disease-specific survival. High-quality …

Objective The management of thyroid nodules with indeterminate cytology (ITN) is still a
challenge. To evaluate the performance of commercial molecular tests for ITN, we performed …

Background Papillary thyroid carcinoma (PTC) is the most frequent histological type of
thyroid carcinoma. Although an increasing number of diagnostic methods have recently …

Papillary thyroid carcinoma (PTC) is a highly prevalent cancer that typically exhibits indolent
behavior and is associated with a favorable prognosis. The treatment of choice is surgical …

Purpose Indeterminate cytology still puzzles clinicians, due to its wide range of oncological
risks. According to the Italian SIAPEC–IAP classification, TIR3B cytology holds up to 30% of …