[HTML][HTML] Blood-brain barrier, blood-brain tumor barrier, and fluorescence-guided neurosurgical oncology: delivering optical labels to brain tumors
E Belykh, KV Shaffer, C Lin, VA Byvaltsev… - Frontiers in …, 2020 - frontiersin.org
Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …
of visualization techniques to complement intraoperative white-light imaging of tumors …
[HTML][HTML] Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results
JT Senders, IS Muskens, R Schnoor, AV Karhade… - Acta …, 2017 - Springer
Background Fluorescence-guided surgery (FGS) is a technique used to enhance
visualization of tumor margins in order to increase the extent of tumor resection in glioma …
visualization of tumor margins in order to increase the extent of tumor resection in glioma …
Safety and tumor specificity of cetuximab-IRDye800 for surgical navigation in head and neck cancer
Purpose: Positive margins dominate clinical outcomes after surgical resections in most solid
cancer types, including head and neck squamous cell carcinoma. Unfortunately, surgeons …
cancer types, including head and neck squamous cell carcinoma. Unfortunately, surgeons …
Label-free neurosurgical pathology with stimulated Raman imaging
The goal of brain tumor surgery is to maximize tumor removal without injuring critical brain
structures. Achieving this goal is challenging as it can be difficult to distinguish tumor from …
structures. Achieving this goal is challenging as it can be difficult to distinguish tumor from …
The value of extent of resection of glioblastomas: clinical evidence and current approach
Glioblastomas (GBM), one of the most common tumors of the central nervous system, are
associated with poor prognosis, even with all the scientific development of the last decades …
associated with poor prognosis, even with all the scientific development of the last decades …
[HTML][HTML] 5-Aminolevulinic acid induced fluorescence is a powerful intraoperative marker for precise histopathological grading of gliomas with non-significant contrast …
Background Intraoperative identification of anaplastic foci in diffusely infiltrating gliomas
(DIG) with non-significant contrast-enhancement on MRI is indispensible to avoid …
(DIG) with non-significant contrast-enhancement on MRI is indispensible to avoid …
[HTML][HTML] Combined-therapeutic strategies synergistically potentiate glioblastoma multiforme treatment via nanotechnology
J Yang, Z Shi, R Liu, Y Wu, X Zhang - Theranostics, 2020 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is a highly aggressive and devastating brain tumor
characterized by poor prognosis and high rates of recurrence. Numerous therapeutic …
characterized by poor prognosis and high rates of recurrence. Numerous therapeutic …
Optical technologies for intraoperative neurosurgical guidance
Biomedical optics is a broadly interdisciplinary field at the interface of optical engineering,
biophysics, computer science, medicine, biology, and chemistry, helping us understand light …
biophysics, computer science, medicine, biology, and chemistry, helping us understand light …
Fluorescent imaging of cancerous tissues for targeted surgery
To maximize tumor excision and minimize collateral damage are the primary goals of cancer
surgery. Emerging molecular imaging techniques have made “image-guided surgery” …
surgery. Emerging molecular imaging techniques have made “image-guided surgery” …
Dual‐modality surface‐enhanced resonance Raman scattering and multispectral optoacoustic tomography nanoparticle approach for brain tumor delineation
Difficulty in visualizing glioma margins intraoperatively remains a major issue in the
achievement of gross total tumor resection and, thus, better clinical outcome of glioblastoma …
achievement of gross total tumor resection and, thus, better clinical outcome of glioblastoma …