Next generation gold drugs and probes: chemistry and biomedical applications

RT Mertens, S Gukathasan, AS Arojojoye… - Chemical …, 2023 - ACS Publications
The gold drugs, gold sodium thiomalate (Myocrisin), aurothioglucose (Solganal), and the
orally administered auranofin (Ridaura), are utilized in modern medicine for the treatment of …

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens

A Evans, KA Kavanagh - Journal of Medical Microbiology, 2021 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the greatest global health challenges of modern
times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of …

Metal complexes, an untapped source of antibiotic potential?

A Frei - Antibiotics, 2020 - mdpi.com
With the widespread rise of antimicrobial resistance, most traditional sources for new drug
compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …

Antimicrobial activity of gold nanoparticles and ionic gold

Y Zhang, TP Shareena Dasari, H Deng… - … Science and Health …, 2015 - Taylor & Francis
Gold, in both nanoparticle (AuNPs) and ionic forms, has been studied for antibiotic activities.
Some of the organic complexes of Au (I & III) ions are antibacterial. AuNPs are antifungal …

Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First In Vivo Experiments

A Frei, AG Elliott, A Kan, H Dinh, S Bräse, AE Bruce… - JACS au, 2022 - ACS Publications
There are currently fewer than 10 antifungal drugs in clinical development, but new fungal
strains that are resistant to most current antifungals are spreading rapidly across the world …

Potential application of gold nanoparticles in food packaging: a mini review

S Paidari, SA Ibrahim - Gold Bulletin, 2021 - Springer
In the past few decades, there have been remarkable advances in our knowledge of gold
nanoparticles (AuNPs) and synthesizing methods. AuNPs have become increasingly …

Recent studies on the antimicrobial activity of transition metal complexes of groups 6–12

S Nasiri Sovari, F Zobi - Chemistry, 2020 - mdpi.com
Antimicrobial resistance is an increasingly serious threat to global public health that requires
innovative solutions to counteract new resistance mechanisms emerging and spreading …

Gold (I) NHC complexes: antiproliferative activity, cellular uptake, inhibition of mammalian and bacterial thioredoxin reductases, and gram‐positive directed …

C Schmidt, B Karge, R Misgeld… - … A European Journal, 2017 - Wiley Online Library
Gold complexes with N‐heterocyclic carbene (NHC) ligands represent a promising class of
metallodrugs for the treatment of cancer or infectious diseases. In this report, the synthesis …

Novel papaverine metal complexes with potential anticancer activities

A Gaber, WF Alsanie, DN Kumar, MS Refat, EM Saied - Molecules, 2020 - mdpi.com
Cancer is one of the leading causes of death worldwide. Although several potential
therapeutic agents have been developed to efficiently treat cancer, some side effects can …

Poly (vinyl) alcohol crosslinked composite packaging film containing gold nanoparticles on shelf life extension of banana

S Chowdhury, YL Teoh, KM Ong, NSR Zaidi… - Food Packaging and …, 2020 - Elsevier
In this work, gold nanoparticles (AuNPs) and graphene oxide (GO) were successfully
incorporated separately into the poly (vinyl) alcohol (PVA) crosslinked composite films …