Biomolecular mechanisms of epileptic seizures and epilepsy: a review

KT Sumadewi, S Harkitasari, DC Tjandra - Acta Epileptologica, 2023 - Springer
Epilepsy is a recurring neurological disease caused by the abnormal electrical activity in the
brain. This disease has caused about 50 new cases in 100,000 populations every year with …

Mitochondrial DNA Leakage and cGas/STING Pathway in Microglia: Crosstalk Between Neuroinflammation and Neurodegeneration

Y Liu, B Zhang, R Duan, Y Liu - Neuroscience, 2024 - Elsevier
Neurodegenerative diseases, characterized by abnormal deposition of misfolded proteins,
often present with progressive loss of neurons. Chronic neuroinflammation is a striking …

Polymorphism of transferrin gene impacts the mediating effects of psychotic symptoms on the relationship between oxidative stress and cognition in patients with …

P Chen, D Wang, M Xiu, D Chen, B Lackey, HE Wu… - Antioxidants, 2022 - mdpi.com
A series of studies indicated that iron distribution that partly derives from transferrin-bound
iron in the peripheral nervous system in the brain may act in processes such as myelination …

Analysis of significance of mitochondrial dysfunction in the pathogenesis of diseases of the central nervous system

OP Sokolik, GO Prozorova - Neuroscience Research Notes, 2022 - neuroscirn.org
One of the promising therapy areas for many diseases of the central nervous system is the
search for agents of selective effect on mitochondria. Both the mitochondria themselves and …

A big picture of the mitochondria-mediated signals: From mitochondria to organism

NV Acar, RK Özgül - Biochemical and Biophysical Research …, 2023 - Elsevier
Mitochondria, well-known for years as the powerhouse and biosynthetic center of the cell,
are dynamic signaling organelles beyond their energy production and biosynthesis …

Cell-Free Mitochondrial DNA as a Novel biomarker for stress-related conditions-Meta-Analysis

A Chattopadhyay, H Tak, BH Naick - Human Gene, 2023 - Elsevier
Mitochondria is a central organelle that regulates various physiological functions of the cell,
like Reactive oxygen species (ROS) generation, apoptosis, and energy metabolism; its …

Inflammatory profile in mitochondrial diseases: A cohort study

G Primiano, D Plantone, G Piro… - European journal …, 2023 - pubmed.ncbi.nlm.nih.gov
Inflammatory profile in mitochondrial diseases: A cohort study Inflammatory profile in
mitochondrial diseases: A cohort study Eur J Neurol. 2023 Oct;30(10):3409-3410. doi …

[HTML][HTML] Mitochondrial dysfunction and oxidative stress in Alzheimer's disease-A step towards mitochondria based therapeutic strategies

KR Aran - Aging and Health Research, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease with reduced cognitive function
due to mitochondrial dysfunction and oxidative stress. Recent studies show that the …

[HTML][HTML] Circulating Cell-free mitochondrial DNA: a potential blood-based biomarker for sarcopenia in patients undergoing maintenance hemodialysis

Z Fan, Y Guo, X Zhong - Medical Science Monitor: International …, 2022 - ncbi.nlm.nih.gov
Background Mitochondrial impairment and exaggerated inflammation are hallmarks of
sarcopenia. Recently, cell-free mitochondrial DNA (cf-mtDNA) has been in the spotlight as …

An examination of psychological stress and its effects on the mitochondrial DNA

P Mirzadeh - 2023 - yorkspace.library.yorku.ca
Background: With improvements in cellular stress measurement, current findings firmly
implicate mitochondrial activity in cell stress reactions. Recent studies have highlighted the …