The interaction between the peripheral immune system and the brain is increasingly being
recognized as an important layer of neuroimmune regulation and plays vital roles in brain …

OTUD5 (OTU Deubiquitinase 5) is a functional cysteine protease with deubiquitinase activity
and is a member of the ovarian tumor protease (OTU) family. OTUD5 is involved in the …

The red sea urchin (Mesocentrotus franciscanus) is one of the Earth's longest-living animals,
reported to live more than 100 years with indeterminate growth, life-long reproduction, and …

Tumor‐associated macrophages (TAMs) are key components of the tumor
microenvironment, and their different polarization states play multiple roles in tumors by …

Background Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting
women of reproductive ages. Our previous study has implicated a possible link between …

Introduction The culture of Pacific oysters (Crassostrea gigas) is of significant socio-
economic importance in the US Pacific Northwest and other temperate regions worldwide …

Due to the lack of biomarkers predictive of response to atezolizumab–bevacizumab, the
standard of care for advanced HCC, we analyzed baseline and early on‐treatment variation …

Chronic varicella zoster virus (VZV) infection induced neuroinflammatory condition is the
critical pathology of postherpetic neuralgia (PHN). The immune escape mechanism of VZV …

Tripartite motif-containing protein 32 (TRIM32) is a member of the tripartite motif family and is
highly conserved from flies to humans. Via its E3 ubiquitin ligase activity, TRIM32 mediates …

ABSTRACT Rickettsia rickettsii (R. rickettsii), the causative agent of Rocky Mountain spotted
fever (RMSF), is the most pathogenic member among Rickettsia spp. Previous studies have …