[HTML][HTML] Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults–an AGePOP review
C Demeester, D Robins, AE Edwina, J Tournoy… - European Journal of …, 2023 - Elsevier
The older population consisting of persons aged 65 years or older is the fastest-growing
population group and also the major consumer of pharmaceutical products. Due to the …
population group and also the major consumer of pharmaceutical products. Due to the …
An update on medication use in older adults: a narrative review
HE Barry, CM Hughes - Current Epidemiology Reports, 2021 - Springer
Abstract Purpose of Review The global phenomenon of population aging is impacting the
health and care needs of society. The use of medications by older adults is acknowledged to …
health and care needs of society. The use of medications by older adults is acknowledged to …
Sex differences in multimorbidity and polypharmacy trends: a repeated cross-sectional study of older adults in Ontario, Canada
Background Multimorbidity is increasing among older adults, but the impact of these recent
trends on the extent and complexity of polypharmacy and possible variation by sex remains …
trends on the extent and complexity of polypharmacy and possible variation by sex remains …
The association of potentially inappropriate medications, polypharmacy and anticholinergic burden with readmission and emergency room revisit after discharge: A …
Aims While certain drug‐use indicators are known to be associated with clinical outcomes,
the relationship is unclear for some highly prevalent conditions in in patients aged≥ 65 …
the relationship is unclear for some highly prevalent conditions in in patients aged≥ 65 …
Prevalence of prescription and non-prescription polypharmacy by frailty and sex among middle-aged and older Canadians
Background Estimates of polypharmacy have primarily been derived from prescription
claims, and less is known about the use of non-prescription medications (alone or in …
claims, and less is known about the use of non-prescription medications (alone or in …
Relationship between frailty and drug use among nursing homes residents: results from the SHELTER study
Abstract Background 1.5–8% of older adults live in nursing homes (NHs), presenting a high
prevalence of frailty and polypharmacy. Aims To investigate the association of frailty with …
prevalence of frailty and polypharmacy. Aims To investigate the association of frailty with …
Trends in anticoagulant use at nursing home admission and variation by frailty and chronic kidney disease among older adults with atrial fibrillation
MA Campitelli, SE Bronskill, A Huang, LC Maclagan… - Drugs & Aging, 2021 - Springer
Background Atrial fibrillation (AF) is relatively common among nursing home residents, and
decisions regarding anticoagulant therapy in this setting may be complicated by resident …
decisions regarding anticoagulant therapy in this setting may be complicated by resident …
Correlates of opioid use among Ontario long-term care residents and variation by pain frequency and intensity: a cross-sectional analysis
A Iacono, MA Campitelli, SE Bronskill, DB Hogan… - Drugs & Aging, 2022 - Springer
Background Chronic non-cancer pain is common among older residents of long-term care
(LTC) homes and often poorly recognized and treated. With heightened concerns regarding …
(LTC) homes and often poorly recognized and treated. With heightened concerns regarding …
Pharmacists' knowledge, perceptions and practices regarding frailty: a cross-sectional survey across practice settings in Canada
Background: Data on Canadian pharmacists' knowledge and perceptions about frailty in
older adults and its assessment in pharmacy practice are scarce. Methods: A cross-sectional …
older adults and its assessment in pharmacy practice are scarce. Methods: A cross-sectional …
'I think we could probably do more': an interview study to explore community pharmacists' experiences and perspectives of frailty and optimising medicines use in frail …
L Faulkner, CM Hughes, HE Barry - Age and Ageing, 2024 - academic.oup.com
Background Community pharmacists potentially have an important role to play in
identification of frailty and delivery of interventions to optimise medicines use for frail older …
identification of frailty and delivery of interventions to optimise medicines use for frail older …