Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics
EM Bressler, S Adams, R Liu, YL Colson… - Clinical and …, 2023 - Wiley Online Library
Background: The intersection of synthetic biology and biomaterials promises to enhance
safety and efficacy in novel therapeutics. Both fields increasingly employ Boolean logic …
safety and efficacy in novel therapeutics. Both fields increasingly employ Boolean logic …
[HTML][HTML] An electrogenetic interface to program mammalian gene expression by direct current
J Huang, S Xue, P Buchmann, AP Teixeira… - Nature …, 2023 - nature.com
Wearable electronic devices are playing a rapidly expanding role in the acquisition of
individuals' health data for personalized medical interventions; however, wearables cannot …
individuals' health data for personalized medical interventions; however, wearables cannot …
Sub-1.4 cm3 capsule for detecting labile inflammatory biomarkers in situ
Transient molecules in the gastrointestinal tract such as nitric oxide and hydrogen sulfide
are key signals and mediators of inflammation. Owing to their highly reactive nature and …
are key signals and mediators of inflammation. Owing to their highly reactive nature and …
Synthetic Gene Circuits for Regulation of Next‐Generation Cell‐Based Therapeutics
AP Teixeira, M Fussenegger - Advanced Science, 2024 - Wiley Online Library
Arming human cells with synthetic gene circuits enables to expand their capacity to execute
superior sensing and response actions, offering tremendous potential for innovative cellular …
superior sensing and response actions, offering tremendous potential for innovative cellular …
Evolution of molecular switches for regulation of transgene expression by clinically licensed gluconate
AP Teixeira, S Xue, J Huang… - Nucleic Acids …, 2023 - academic.oup.com
Synthetic biology holds great promise to improve the safety and efficacy of future gene and
engineered cell therapies by providing new means of endogenous or exogenous control of …
engineered cell therapies by providing new means of endogenous or exogenous control of …
[HTML][HTML] Designing transparent piezoelectric metasurfaces for adaptive optics
Simultaneously generating various motion modes with high strains in piezoelectric devices
is highly desired for high-technology fields to achieve multi-functionalities. However …
is highly desired for high-technology fields to achieve multi-functionalities. However …
Microneedle‐Mediated Cell Therapy
Microneedles have emerged as a promising platform for transdermal drug delivery with
prominent advantages, such as enhanced permeability, mitigated pain, and improved …
prominent advantages, such as enhanced permeability, mitigated pain, and improved …
Advancing piezoelectric 2D nanomaterials for applications in drug delivery systems and therapeutic approaches
Precision drug delivery and multimodal synergistic therapy are crucial in treating diverse
ailments, such as cancer, tissue damage, and degenerative diseases. Electrodes that emit …
ailments, such as cancer, tissue damage, and degenerative diseases. Electrodes that emit …
Electro-biofabrication. Coupling electrochemical and biomolecular methods to create functional bio-based hydrogels
Twenty years ago, this journal published a review entitled “Biofabrication with Chitosan”
based on the observations that (i) chitosan could be electrodeposited using low voltage …
based on the observations that (i) chitosan could be electrodeposited using low voltage …
Ultrasonic Electroporation for Cells Grown on Piezoelectric Film Composed of Hydroxyapatite Nanowire and PVDF
The delivery of cell impermeable exogenous material into live cells by external stimuli is
critical for both biological research and therapeutic applications. Although electroporation …
critical for both biological research and therapeutic applications. Although electroporation …