[HTML][HTML] Generation of potent cellular and humoral immunity against SARS-CoV-2 antigens via conjugation to a polymeric glyco-adjuvant
The SARS-CoV-2 virus has caused an unprecedented global crisis, and curtailing its spread
requires an effective vaccine which elicits a diverse and robust immune response. We have …
requires an effective vaccine which elicits a diverse and robust immune response. We have …
[HTML][HTML] Impact of COVID-19 in individuals with and without pre-existent digestive disorders with a particular focus on elderly patients
Abstract Coronavirus disease 2019 (COVID-19) has several extrapulmonary symptoms.
Gastrointestinal (GI) symptoms are among the most frequent clinical manifestations of …
Gastrointestinal (GI) symptoms are among the most frequent clinical manifestations of …
Elevated monocyte to lymphocyte ratio and increased mortality among patients with chronic kidney disease hospitalized for COVID-19
R Davila-Collado, O Jarquin-Duran… - Journal of personalized …, 2021 - mdpi.com
Chronic kidney disease (CKD) constitutes a major health problem and one of the leading
causes of death worldwide. Patients with CKD have impaired immune functions that …
causes of death worldwide. Patients with CKD have impaired immune functions that …
Клиническая картина и факторы, ассоциированные с неблагоприятными исходами у госпитализированных пациентов с новой коронавирусной инфекцией …
Клиническая картина и факторы, ассоциированные с неблагоприятными и Page 1 4 ISSN
0022-9040. Кардиология. 2021;61(2). DOI: 10.18087/cardio.2021.2.n1532 §РЕДАКЦИОННЫЕ …
0022-9040. Кардиология. 2021;61(2). DOI: 10.18087/cardio.2021.2.n1532 §РЕДАКЦИОННЫЕ …
Asthma in patients with coronavirus disease 2019: a systematic review and meta-analysis
L Shi, J Xu, W Xiao, Y Wang, Y Jin, S Chen… - Annals of Allergy …, 2021 - Elsevier
Background It is unclear whether asthma has an influence on contracting coronavirus
disease 2019 (COVID-19) or having worse outcomes from COVID-19 disease. Objective To …
disease 2019 (COVID-19) or having worse outcomes from COVID-19 disease. Objective To …
Drug–drug interactions between treatment specific pharmacotherapy and concomitant medication in patients with COVID-19 in the first wave in Spain
MD Cantudo-Cuenca, A Gutierrez-Pizarraya… - Scientific Reports, 2021 - nature.com
Primary aim was to assess prevalence and severity of potential and real drug–drug
interactions (DDIs) among therapies for COVID-19 and concomitant medications in …
interactions (DDIs) among therapies for COVID-19 and concomitant medications in …
Characteristics and risk factors associated with mortality in a multicenter Spanish cohort of patients with COVID-19 pneumonia
JR Muñoz-Rodríguez, FJ Gómez-Romero… - Archivos de …, 2021 - Elsevier
Introduction Spain is one of the countries with the highest number of COVID-19 patients.
Unfortunately, few data for regions are available. Objectives This study aimed to describe …
Unfortunately, few data for regions are available. Objectives This study aimed to describe …
A clinical decision web to predict ICU admission or death for patients hospitalised with COVID-19 using machine learning algorithms
R Aznar-Gimeno, LM Esteban… - International Journal of …, 2021 - mdpi.com
The purpose of the study was to build a predictive model for estimating the risk of ICU
admission or mortality among patients hospitalized with COVID-19 and provide a user …
admission or mortality among patients hospitalized with COVID-19 and provide a user …
Use of rituximab and the risk of adverse clinical outcomes in COVID-19 patients with systemic rheumatic disease
We read with interest the descriptive study by Loarce-Martos et al.[1] to investigate the
clinical characteristics and outcomes of patients with systemic rheumatic disease receiving …
clinical characteristics and outcomes of patients with systemic rheumatic disease receiving …
Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate
E Prieto-Fernández, L Egia-Mendikute… - Emerging Microbes & …, 2021 - Taylor & Francis
ABSTRACT A main clinical parameter of COVID-19 pathophysiology is hypoxia. Here we
show that hypoxia decreases the attachment of the receptor-binding domain (RBD) and the …
show that hypoxia decreases the attachment of the receptor-binding domain (RBD) and the …