Review on near-infrared heptamethine cyanine dyes as theranostic agents for tumor imaging, targeting, and photodynamic therapy

C Shi, JB Wu, D Pan - Journal of biomedical optics, 2016 - spiedigitallibrary.org
A class of near-infrared fluorescence (NIRF) heptamethine cyanine dyes that are taken up
and accumulated specifically in cancer cells without chemical conjugation have recently …

Explorations into the Effect of meso‐Substituents in Tricarbocyanine Dyes: A Path to Diverse Biomolecular Probes and Materials

RM Exner, F Cortezon‐Tamarit… - Angewandte Chemie …, 2021 - Wiley Online Library
Polymethine cyanine dyes have been widely recognized as promising chemical tools for a
range of life science and biomedical applications, such as fluorescent staining of DNA and …

Near-infrared pH-activatable fluorescent probes for imaging primary and metastatic breast tumors

H Lee, W Akers, K Bhushan, S Bloch… - Bioconjugate …, 2011 - ACS Publications
Highly tumor selective near-infrared (NIR) pH-activatable probe was developed by
conjugating pH-sensitive cyanine dye to a cyclic arginine-glycine-aspartic acid (cRGD) …

Computational Design, Synthesis, and Photochemistry of Cy7‐PPG, an Efficient NIR‐Activated Photolabile Protecting Group for Therapeutic Applications

G Alachouzos, AM Schulte, A Mondal… - Angewandte …, 2022 - Wiley Online Library
Abstract Photolabile Protecting Groups (PPGs) are molecular tools used, for example, in
photopharmacology for the activation of drugs with light, enabling spatiotemporal control …

Selective imaging and cancer cell death via pH switchable near-infrared fluorescence and photothermal effects

J Zhang, Z Liu, P Lian, J Qian, X Li, L Wang, W Fu… - Chemical …, 2016 - pubs.rsc.org
Accurately locating and eradicating sporadically distributed cancer cells whilst minimizing
damage to adjacent normal tissues is vital in image-guided tumor ablation. In this work, we …

Design and synthesis of polymer-functionalized NIR fluorescent dyes–magnetic nanoparticles for bioimaging

SK Yen, D Janczewski, JL Lakshmi, SB Dolmanan… - ACS …, 2013 - ACS Publications
The fluorescent probes having complete spectral separation between absorption and
emission spectra (large Stokes shift) are highly useful for solar concentrators and …

Near‐Infrared Fluorophores Based on Heptamethine Cyanine Dyes: From Their Synthesis and Photophysical Properties to Recent Optical Sensing and Bioimaging …

NG Medeiros, CA Braga, VS Câmara… - Asian Journal of …, 2022 - Wiley Online Library
This review summarizes diverse synthetic methodologies to prepare a wide range of
heptamethine cyanine dyes, including symmetrical, unsymmetrical, and meso‐substituted …

Heptamethine cyanine–based application for cancer theranostics

L Zhang, H Jia, X Liu, Y Zou, J Sun, M Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer is the most common life-threatening malignant disease. The future of personalized
cancer treatments relies on the development of functional agents that have tumor-targeted …

Mitochondria‐targeting IR‐780 dye and its derivatives: synthesis, mechanisms of action, and theranostic applications

C Zhang, L Long, C Shi - Advanced Therapeutics, 2018 - Wiley Online Library
Mitochondria are important targets in diverse physiological and pathological conditions
associated with cell survival and death. The characterization of mitochondria‐targeting …

Water‐Soluble Red‐Emitting Distyryl‐Borondipyrromethene (BODIPY) Dyes for Biolabeling

S Niu, C Massif, G Ulrich, PY Renard… - … A European Journal, 2012 - Wiley Online Library
A series of water‐soluble red‐emitting distyryl‐borondipyrromethene (BODIPY) dyes were
designed and synthesized by using three complementary approaches aimed at introducing …