Transforming growth factor-β signaling: from tissue fibrosis to therapeutic opportunities

LL Ren, XJ Li, TT Duan, ZH Li, JZ Yang… - Chemico-biological …, 2023 - Elsevier
Fibrosis refers to the excessive deposition of extracellular matrix components in the
processes of wound repair or tissue regeneration after tissue damage. Fibrosis occurs in …

[HTML][HTML] Active clinical trials in hepatic encephalopathy: something old, something new and something borrowed

T Balzano - Neurochemical Research, 2023 - Springer
Hepatic encephalopathy (HE) is a potentially reversible neurocognitive syndrome that
occurs in patients with acute or chronic liver disease. Currently, most of the therapies for HE …

[HTML][HTML] Systemic pharmacological verification of Salvia miltiorrhiza-Ginseng Chinese herb pair in inhibiting spontaneous breast cancer metastasis

H Han, C Qian, G Zong, H Liu, F Wang, R Tao… - Biomedicine & …, 2022 - Elsevier
Breast cancer is the most commonly diagnosed cancer in the world, and metastasis is often
the main cause of death in breast cancer patients. Salvia miltiorrhiza-Ginseng (SG) herb pair …

[HTML][HTML] JBB attenuates acute and chronic alcoholic liver injury by regulating the NFκB, KEAP1, and HIF1 pathways

Y Fu, Z Zeng, S Feng, Y Chen, Q Ding, Y Shi - Journal of Functional Foods, 2023 - Elsevier
Alcoholic liver disease (ALD) is a liver injury caused by chronic or binge alcohol
consumption. Jiubanban (JBB) is a 10-edible-herb-formula. The current study investigated …

[PDF][PDF] Advances in traditional Chinese medicine for liver disease therapy in 2021

JY Luo, JB Liao, YM Wang, J Zhao, X Xie… - Traditional Medical …, 2022 - tmrjournals.cn
Liver diseases and their co-morbidities represent a major public health problem. Owing to its
progressive pathogenesis and lack of effective treatment, liver disease has become one of …

[HTML][HTML] Comparative Pharmacokinetics of Three Bioactive Diterpenoids of Rabdosia serra Extract in Normal and Con A-Induced Liver Injury Rats Using UPLC-MS …

F Liu, Y Zeng, P Dai, K Huang, K Zhang… - Frontiers in …, 2022 - frontiersin.org
Rabdosia serra (Maxim.) Hara (R. serra), one of the source plants of “Xihuangcao”, has
been widely used as a Chinese folk herb with the concomitant function of both medicine and …

An integrated network pharmacology approach reveals that Ampelopsis grossedentata improves alcoholic liver disease via TLR4/NF-κB/MLKL pathway.

P Qiu, A Mi, C Hong, S Huang, Q Ma, Q Luo, J Qiu… - Phytomedicine, 2024 - Elsevier
Background Alcohol-related liver damage is the most prevalent chronic liver disease, which
creates a heavy public health burden worldwide. The leaves of Ampelopsis grossedentata …

[HTML][HTML] Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking

Y Tan, F Zhang, X Fan, S Lu, Y Liu, Z Wu, Z Huang… - Chinese Medicine, 2023 - Springer
Background Yinzhihuang granules (YZHG) is a commonly used Chinese patent medicine for
the treatment of liver disease. However, the mechanism of YZHG in alcoholic liver disease …

Recent progress on the application of compound formulas of traditional Chinese medicine in clinical trials and basic research in vivo for chronic liver disease

F Xu, H Zhang, J Chen, J Zhan, P Liu, W Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Chronic liver diseases mainly include chronic viral liver
disease, metabolic liver disease, cholestatic liver disease (CLD), autoimmune liver disease …

New perspectives on chemokines in hepatocellular carcinoma therapy: a critical pathway for natural products regulation of the tumor microenvironment

X Ruishi, X Linyi, B Yunfan, Y Wenbo… - Frontiers in …, 2024 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the most common primary neoplasms of the liver
and one of the most common solid tumors in the world. Its global incidence is increasing and …