[HTML][HTML] MSC based gene delivery methods and strategies improve the therapeutic efficacy of neurological diseases

H Zhou, Y He, W Xiong, S Jing, X Duan, Z Huang… - Bioactive materials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are promising seed cells for neural regeneration therapy
owing to their plasticity and accessibility. They possess several inherent characteristics …

Stem cells: a historical review about biological, religious, and ethical issues

IA Charitos, A Ballini, S Cantore… - Stem Cells …, 2021 - Wiley Online Library
Stem cells can be used to replace damaged cells or regenerate organs and have
broadened our knowledge of the development and progression of certain diseases. Despite …

The role of biomaterials in peripheral nerve and spinal cord injury: a review

B Kaplan, S Levenberg - International journal of molecular sciences, 2022 - mdpi.com
Peripheral nerve and spinal cord injuries are potentially devastating traumatic conditions
with major consequences for patients' lives. Severe cases of these conditions are currently …

Platelet-rich plasma-derived exosomes boost mesenchymal stem cells to promote peripheral nerve regeneration

Y Zhang, D Yi, Q Hong, J Cao, X Geng, J Liu… - Journal of Controlled …, 2024 - Elsevier
Peripheral nerve injury (PNI) remains a severe clinical problem with debilitating
consequences. Mesenchymal stem cell (MSC)-based therapy is promising, but the problems …

Low-stiffness hydrogels promote peripheral nerve regeneration through the rapid release of exosomes

Z Liu, H Tong, J Li, L Wang, X Fan, H Song… - … in Bioengineering and …, 2022 - frontiersin.org
A hydrogel system loaded with mesenchymal stem cell–derived exosome (MSC-Exos) is an
attractive new tool for tissue regeneration. However, the effect of the stiffness of exosome …

Cell-free therapy based on extracellular vesicles: a promising therapeutic strategy for peripheral nerve injury

MS Namini, F Daneshimehr, N Beheshtizadeh… - Stem Cell Research & …, 2023 - Springer
Peripheral nerve injury (PNI) is one of the public health concerns that can result in a loss of
sensory or motor function in the areas in which injured and non-injured nerves come …

Beyond the limiting gap length: peripheral nerve regeneration through implantable nerve guidance conduits

ER Riva, M Özkan, E Contreras, S Pawar… - Biomaterials …, 2024 - pubs.rsc.org
Peripheral nerve damage results in the loss of sensorimotor and autonomic functions, which
is a significant burden to patients. Furthermore, nerve injuries greater than the limiting gap …

The application of collagen in the repair of peripheral nerve defect

X Li, X Zhang, M Hao, D Wang, Z Jiang… - … in Bioengineering and …, 2022 - frontiersin.org
Collagen is a natural polymer expressed in the extracellular matrix of the peripheral nervous
system. It has become increasingly crucial in peripheral nerve reconstruction as it was …

[HTML][HTML] Platelet lysate promotes proliferation and angiogenic activity of dental pulp stem cells via store-operated Ca2+ entry

X Liao, M Chen, Y Zhang, S Li, Y Li, Y He, Y Zhao… - Nano TransMed, 2023 - Elsevier
Aims Dental pulp stem cells (DPSCs) had been widely used in nerve tissue engineering.
However, the low cell survival and invalid differentiation were urgent problems to be solved …

Research hotspots and trends of peripheral nerve injuries based on web of science from 2017 to 2021: a bibliometric analysis

S Zhang, M Huang, J Zhi, S Wu, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Background Peripheral nerve injury (PNI) is very common in clinical practice, which often
reduces the quality of life of patients and imposes a serious medical burden on society …