“Organ‐on‐a‐chip” systems integrate microengineering, microfluidic technologies, and
biomimetic principles to create key aspects of living organs faithfully, including critical …

Last decade's advancements in optofluidics allowed obtaining an ever increasing
integration of different functionalities in lab on chip devices to culture, analyze, and …

Here we describe a robust, microfluidic technique to generate and analyze 3D tumor
spheroids, which resembles tumor microenvironment and can be used as a more effective …

The development of novel cellular models that can replace animals in preclinical trials of
drug candidates is one of the major goals of cell engineering. Current in vitro screening …

Rational development of more physiologic in vitro models includes the design of robust and
flexible 3D-microtissue-based multi-tissue devices, which allow for tissue–tissue …

Multicellular spheroids are useful models of mammalian tissue for studies of cell
proliferation, differentiation, replacement therapies and drug action. Having a size of 100 …

Bacterial aggregation and patchiness play an important role in a variety of ecological
processes such as competition, adaptation, epidemics, and succession. Here, we …

Nanomedicine has brought great advances for drug delivery by improving the safety and
efficacy of pharmaceuticals. However, many nanomaterials showing good distribution …

Intense acoustically driven microcentrifugation flows are employed to enhance the assembly
of cellular spheroids in the microwell of a tissue culture well plate. This ability to interface …

Cancer stem cells reside in a distinct microenvironment called niche. The reciprocal
interactions between cancer stem cells and niche contribute to the maintenance and …