Molecular mechanisms of migraine: Nitric oxide synthase and neuropeptides

N Karsan, H Gosalia, PJ Goadsby - International Journal of Molecular …, 2023 - mdpi.com
Migraine is a common condition with disabling attacks that burdens people in the prime of
their working lives. Despite years of research into migraine pathophysiology and …

The role of microRNA in migraine: a systemic literature review

O Grodzka, S Słyk, I Domitrz - Cellular and Molecular Neurobiology, 2023 - Springer
Migraine is a common primary headache disorder, affecting about 14% of the population.
Importantly, it was indicated as the second cause of disability globally and the leading cause …

The epigenetics of migraine

F Zobdeh, II Eremenko, MA Akan, VV Tarasov… - International Journal of …, 2023 - mdpi.com
Migraine is a complex neurological disorder and a major cause of disability. A wide range of
different drug classes such as triptans, antidepressants, anticonvulsants, analgesics, and …

Reduced plasma calcitonin gene-related peptide level identified in cluster headache: A prospective and controlled study

AS Petersen, N Lund, K Meßlinger… - …, 2024 - journals.sagepub.com
Background The role of calcitonin gene-related peptide (CGRP) in the cyclic pattern of
cluster headache is unclear. To acquire biological insight and to comprehend why only …

[HTML][HTML] Different aspects of aging in migraine

M Fila, E Pawlowska, J Szczepanska… - Aging and Disease, 2023 - ncbi.nlm.nih.gov
Migraine is a common neurological disease displaying an unusual dependence on age. For
most patients, the peak intensity of migraine headaches occurs in 20s and lasts until 40s, but …

Real-life experiences with galcanezumab and predictors for treatment response in Turkey

P Yalinay Dikmen, B Baykan, D Uludüz, A Özge… - BMC neurology, 2023 - Springer
Background The complexity of clinical practice extends far beyond the controlled settings of
trials, and there is a need for real-world studies aimed at identifying which patients will …

Characteristics associated with response to subcutaneously administered anti‐CGRP monoclonal antibody medications in a real‐world community cohort of persons …

BA Chase, I Semenov, S Rubin… - … : The Journal of …, 2024 - Wiley Online Library
Objective To evaluate response to anti‐calcitonin gene–related peptide (CGRP) migraine
preventives in a real‐world community cohort of persons living with migraine and to identify …

Serum VEGF and CGRP Biomarkers: Relationships with Pain Intensity, Electric Pain, Pressure Pain Threshold, and Clinical Symptoms in Fibromyalgia—An …

RM Tapia-Haro, F Molina, A Rus… - International Journal of …, 2023 - mdpi.com
Fibromyalgia (FM) is a multifactorial syndrome, mainly characterized by chronic widespread
pain, whose physiopathology is yet to be determined. Reliable biomarkers for FM and how …

Epigenetic Connections of the TRPA1 Ion Channel in Pain Transmission and Neurogenic Inflammation—a Therapeutic Perspective in Migraine?

M Fila, E Pawlowska, J Szczepanska, J Blasiak - Molecular Neurobiology, 2023 - Springer
Persistent reprogramming of epigenetic pattern leads to changes in gene expression
observed in many neurological disorders. Transient receptor potential cation channel …

Influences of Genetic and Environmental Factors on Chronic Migraine: A Narrative Review

PK Yeh, YC An, KS Hung, FC Yang - Current Pain and Headache Reports, 2024 - Springer
Abstract Purpose of Review In this narrative review, we aim to summarize recent insights
into the complex interplay between environmental and genetic factors affecting the etiology …