Validating RRP12 expression and its prognostic significance in HCC based on data mining and bioinformatics methods

C Wei, B Wang, ZH Chen, H Xiao, L Tang… - Frontiers in …, 2022 - frontiersin.org
RRP12 (ribosomal RNA processing 12 homolog) is a nucleolar protein involved in the
maturation and transport of eukaryotic ribosomal subunits and is a type of RNA binding …

Novel GSK-3 kinase inhibitor Pym-5 induces GSK-3β rather than GSK-3α-dependent melanogenesis in murine melanoma cells

Q Jia, L Tao, Y Zhou, L Song, Z Wei, T Lu… - Journal of …, 2022 - Elsevier
Background Glycogen synthase kinase-3 (GSK-3) inhibitors are considered to activate Wnt/β-
Catenin, which remains a controversial topic in melanoma treatment. Objective Here, we …

Network-based approach elucidates critical genes in BRCA subtypes and chemotherapy response in Triple Negative Breast Cancer

P Agrawal, N Jain, V Gopalan, A Timon, A Singh… - Iscience, 2024 - cell.com
Breast cancers (BRCA) exhibit substantial transcriptional heterogeneity, posing a significant
clinical challenge. The global transcriptional changes in a disease context, however, are …

KDM2B is required for ribosome biogenesis and its depletion unequally affects mRNA translation

V Anastas, E Chavdoula, A La Ferlita, B Soysal… - bioRxiv, 2024 - biorxiv.org
ABSTRACT KDM2B is a JmjC domain lysine demethylase, which promotes cell
immortalization, stem cell self-renewal and tumorigenesis. Here we employed a multi-omics …

启动子低甲基化介导NOL9 过表达促进肝癌细胞增殖.

陈希瑶, 许镇, 邬喆斌, 张博翔, 彭亮… - Journal of New …, 2023 - search.ebscohost.com
目的探讨核仁蛋白9 (NOL9) 在肝癌中的表达和对肝癌细胞增殖的影响, 进一步阐明NOL9
在肝癌中表达上调的分子机制. 方法选择7 例肝癌患者的手术标本(癌组织和癌旁组织) …

Transcriptional Control Leading to Clinical Outcomes in Breast Cancer Cases

A Aftab, R Khan, U Hameed, T Abbas… - Breast Cancer: From …, 2022 - Springer
Transcription is an important event that use information from a gene and make its protein.
Specific transcription factors are involved in the process that plays a role in generating gene …

[HTML][HTML] BMH-21

SC Kammerud, BJ Metge, AR Elhamamsy, SE Weeks… - selitrectinibinhibitor.com
The term “nutraceutical” was first coined by Dr. Stephen De Felice in 1989 [1]. Nutraceuticals
have been used to prevent and/or treat diseases and increase wellness since ancient times …