Lysosomal glucose sensing and glycophagy in metabolism

MC Mancini, RC Noland, JJ Collier, SJ Burke… - Trends in Endocrinology …, 2023 - cell.com
Lysosomes are cellular organelles that function to catabolize both extra-and intracellular
cargo, act as a platform for nutrient sensing, and represent a core signaling node integrating …

Lipid and glucose metabolism in senescence

B Liu, Q Meng, X Gao, H Sun, Z Xu, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Senescence is an inevitable biological process. Disturbances in glucose and lipid
metabolism are essential features of cellular senescence. Given the important roles of these …

Nobiletin Ameliorates Aging of Chicken Ovarian Prehierarchical Follicles by Suppressing Oxidative Stress and Promoting Autophagy

J Bai, X Wang, Y Chen, Q Yuan, Z Yang, Y Mi, C Zhang - Cells, 2024 - mdpi.com
With the increase in the age of laying chickens, the aging of follicles is accelerated, and the
reproductive ability is decreased. Increased oxidative stress and mitochondrial malfunction …

MFN2 regulates progesterone biosynthesis and proliferation of granulosa cells during follicle selection in hens

Y Hou, J Hu, J Li, H Li, Y Lu… - Journal of Cellular …, 2024 - Wiley Online Library
Follicle selection in hens refers to a biological process that only one small yellow follicle
(SYF) is selected daily or near‐daily for following hierarchical development (from F5/F6 to …

The association and application of sonodynamic therapy and autophagy in diseases

F Chen, Q Xue, N He, X Zhang, S Li, C Zhao - Life Sciences, 2023 - Elsevier
Sonodynamic therapy (SDT) is a new non-invasive treatment method proposed based on
photodynamic therapy (PDT). It has advantages such as high precision, strong tissue …

The follicle-stimulating hormone triggers rapid changes in mitochondrial structure and function in porcine cumulus cells

A Lounas, Y Breton, A Lebrun, I Laflamme… - Scientific Reports, 2024 - nature.com
Oocyte maturation is a key process during which the female germ cell undergoes
resumption of meiosis and completes its preparation for embryonic development including …

The regulatory role of PI3K in ageing-related diseases

Y Liu, Q Liu, Z Zhang, Y Yang, Y Zhou, H Yan… - Ageing Research …, 2023 - Elsevier
Ageing is a physiological/pathological process accompanied by the progressive damage of
cell function, triggering various ageing-related disorders. Phosphatidylinositol 3-kinase …

[HTML][HTML] THSG alleviates cerebral ischemia/reperfusion injury via the GluN2B–CaMKII–ERK1/2 pathway

T Liu, J Shi, D Wu, D Li, Y Wang, J Liu, P Meng, L Hu… - Phytomedicine, 2024 - Elsevier
Background The potential therapeutic targeting of PINK1-PARK2-mediated mitophagy
against cerebral ischemia/reperfusion (CI/R) injury involves the pathophysiological …

Autophagy meets aging: an overview

A Picca, E Marzetti, C Leeuwenburgh - Cells, 2023 - mdpi.com
Aging is characterized by biological disarrangements that increase vulnerability to stressors,
the development of chronic diseases (eg, diabetes, cardiovascular disease, cancer …

Mechanisms of mitochondrial dysfunction in ovarian aging and potential interventions

W Ju, Y Zhao, Y Yu, S Zhao, S Xiang… - Frontiers in …, 2024 - frontiersin.org
Mitochondria plays an essential role in regulating cellular metabolic homeostasis,
proliferation/differentiation, and cell death. Mitochondrial dysfunction is implicated in many …