[HTML][HTML] Solid and Liquid Surface-Supported Bacterial Membrane Mimetics as a Platform for the Functional and Structural Studies of Antimicrobials

S Li, R Ren, L Lyu, J Song, Y Wang, TW Lin, AL Brun… - Membranes, 2022 - mdpi.com
Increasing antibiotic resistance has provoked the urgent need to investigate the interactions
of antimicrobials with bacterial membranes. The reasons for emerging antibiotic resistance …

Biocompatible antimicrobial colistin loaded calcium phosphate nanoparticles for the counteraction of biofilm formation in cystic fibrosis related infections

M Iafisco, F Carella, L Degli Esposti… - Journal of Inorganic …, 2022 - Elsevier
The use of inhalable nanoparticles (NPs) for cystic fibrosis (CF) has been advocated as a
promising tool to improve the efficacy of antimicrobials taking advantage of their ability to …

Carbon-in-carbon: Hybrid carbonized nanomaterials with multifunctional activities for the treatment of endophthalmitis

HJ Jian, YR Chiou, A Anand, CF Chen, DHK Ma… - Chemical Engineering …, 2024 - Elsevier
Infectious endophthalmitis (EO) is a severe eye condition characterized by inflammation of
the eye's internal fluids and tissues, often resulting from infection by bacteria or fungi …

[HTML][HTML] Polyphosphate kinase regulates LPS structure and polymyxin resistance during starvation in E. coli

K Baijal, I Abramchuk, CM Herrera, TF Mah… - Plos …, 2024 - journals.plos.org
Polyphosphates (polyP) are chains of inorganic phosphates that can reach over 1,000
residues in length. In Escherichia coli, polyP is produced by the polyP kinase (PPK) and is …

The use of combination therapy for the improvement of colistin activity against bacterial biofilm

AT Jalil, RTA Alrawe, MA Al-Saffar… - Brazilian Journal of …, 2024 - Springer
Colistin is used as a last resort for the management of infections caused by multi-drug
resistant (MDR) bacteria. However, the use of this antibiotic could lead to different side …

[HTML][HTML] Alkyl deoxyglycoside-polymyxin combinations against critical priority carbapenem-resistant gram-negative bacteria

AM de Matos, P Calado, M Miranda, R Almeida… - Scientific Reports, 2024 - nature.com
The escalating antimicrobial resistance crisis urges the development of new antibacterial
treatments with innovative mechanisms of action, particularly against the critical priority …

Changes in fluidity of the E. coli outer membrane in response to temperature, divalent cations and polymyxin‐B show two different mechanisms of membrane fluidity …

LD Ginez, A Osorio, R Vázquez‐Ramírez… - The FEBS …, 2022 - Wiley Online Library
The outer membrane (OM) is an essential component of the Gram‐negative bacterial cell
envelope. Restricted diffusion of integral OM proteins and lipopolysaccharide (LPS) that …

Bioluminescent test systems based on firefly luciferase for studying stress effects on living cells

GY Lomakina, NN Ugarova - Biophysical Reviews, 2022 - Springer
The bioluminescent luciferin-luciferase reaction is based on the oxidation of D-luciferin by
oxygen in the presence of ATP and magnesium ions, catalyzed by firefly luciferase. The …

Occurrence and distribution of antimicrobial resistance genes in the soil of an industrial park in China: A metagenomics survey

B Zheng, W Liu, H Xu, J Li, X Jiang - Environmental Pollution, 2021 - Elsevier
As zoned areas of industries, industrial parks have great impacts on the environment.
Several studies have demonstrated that chemical compounds and heavy metals released …

A peptide selectively recognizes Gram-negative bacteria and forms a bacterial extracellular trap (BET) through interfacial self-assembly

XL Sha, GT Lv, QH Chen, X Cui, L Wang… - Journal of Materials …, 2024 - pubs.rsc.org
An innate immune system intricately leverages unique mechanisms to inhibit colonization of
external invasive Bacteria, for example human defensin-6, through responsive …