Objectives Metallo-β-lactamase (MBL)-producing Enterobacterales are a major challenge
worldwide due to limited treatment options. Aztreonam-avibactam (ATM-AVI), which is under …

Introduction Polymyxin resistance caused by the plasmid-mediated mcr-1 gene in gram-
negative bacilli poses a huge threat to our health. In recent years, many regions have …

Antibiotic-resistant ESKAPE bacteria have become a significant threat to human health due
to the ineffectiveness of clinically used broad-spectrum antibiotics. Combination therapy of …

Antibiotics are the most crucial drugs for fighting bacterial infection, widely used to treat and
prevent such diseases. Even though these are used against bacterial infections, some …

Affinity describes the non-covalent but selective interaction between an affinity binder (eg,
proteins, antibiotics, or antibodies) and its counterpart (eg, bacteria). These affinity binders …

Klebsiella pneumoniae is one of the significant opportunistic pathogens which cause both
nosocomial and community-acquired infections. This study focuses on the molecular …

Polymer membranes play an important role in various filtration processes. The modification
of a polyamide membrane surface by one-component Zn and ZnO coatings and two …

Purpose In septic shock patients, pathogens and excessive endotoxins continuously
overstimulate the host's immune system with a cytokine storm that can lead to multi-organ …

Antimicrobial resistance is a global health concern across the world and it is foreseen to
swell if no actions are taken now. To help curbing this well announced crisis different …