Ferroptosis-dependent extracellular vesicles from macrophage contribute to asbestos-induced mesothelial carcinogenesis through loading ferritin

F Ito, K Kato, I Yanatori, T Murohara, S Toyokuni - Redox Biology, 2021 - Elsevier
Asbestos-associated diseases remain a social burden worldwide. Our previous studies
identified asbestos-induced iron-rich milieu for mesothelial cells with ceaseless macrophage …

Protective effects of lemon flavonoids on oxidative stress in diabetic rats

Y Miyake, K Yamamoto, N Tsujihara, T Osawa - Lipids, 1998 - Springer
The effects of lemon flavonoids, as crude flavonoids prepared from lemon juice, were
investigated in diabetic rats. The oxidative stress of eriocitrin (eriodictyol 7-O-β-rutinoside) …

Possible action mechanism for curcumin in pre-cancerous lesions based on serum and salivary markers of oxidative stress

B Rai, J Kaur, R Jacobs, J Singh - Journal of oral science, 2010 - jstage.jst.go.jp
Extensive research within the past halfcentury has indicated that curcumin
(diferuloylmethane), a yellow pigment in curry powder, exhibits anti-oxidant, anti …

Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy

A Kikuchi, A Takeda, H Onodera, T Kimpara… - Neurobiology of …, 2002 - Elsevier
8-hydroxy-2′-deoxyguanosine (8-OHdG) or 8-hydroxyguanosine (8-OHG), a product of
oxidized DNA or RNA, is a good marker of oxidative cellular damage. In this study, we …

Heme oxygenase–1 deficiency: The first autopsy case

A Kawashima, Y Oda, A Yachie, S Koizumi, I Nakanishi - Human pathology, 2002 - Elsevier
This article describes the first autopsy case of heme oxygenase (HO)-1 deficiency. A 6-year-
old boy who presented with growth retardation; anemia; leukocytosis; thrombocytosis; …

DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons …

BW Kim, YE Jeong, M Wong, LJ Martin - Acta Neuropathologica …, 2020 - Springer
DNA damage is implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS).
However, relationships between DNA damage accumulation, DNA damage response …

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress: identification of proteasomes as target molecules

K Okada, C Wangpoengtrakul, T Osawa… - Journal of Biological …, 1999 - ASBMB
Oxidative stress is associated with important pathophysiological events in a variety of
diseases. It has been postulated that free radicals and lipid peroxidation products generated …

Salivary analysis in oral cancer patients: DNA and protein oxidation, reactive nitrogen species, and antioxidant profile

G Bahar, R Feinmesser, T Shpitzer, A Popovtzer… - Cancer, 2007 - Wiley Online Library
BACKGROUND. Free radicals such as reactive oxygen species (ROS) and reactive nitrogen
species (RNS), which induce oxidative and nitrative stress, are main contributors to oral …

Tomato sauce supplementation and prostate cancer: lycopene accumulation and modulation of biomarkers of carcinogenesis

P Bowen, L Chen… - Experimental …, 2002 - journals.sagepub.com
As part of a randomized placebo-controlled study to evaluate the effect of lycopene
supplementation on DNA damage in men with prostate cancer, a nonrandomized 5th arm …

New biomarker evidence of oxidative DNA damage in patients with non‐insulin‐dependent diabetes mellitus

J Leinonen, T Lehtimäki, S Toyokuni, K Okada… - FEBS …, 1997 - Wiley Online Library
Urinary 8‐hydroxy‐2′‐deoxyguanosine (8‐OHdG) has been reported to serve as a
sensitive biomarker of oxidative DNA damage and also of oxidative stress. We have …