Objective: To determine the effects of oxidative stress on the quality of oocytes and embryos,
8-hydroxy-2′-deoxyguanosine (8-OHdG) in granulosa cells was quantitatively studied …

Arginine rich, mutated in early stage of tumors (ARMET) was first identified as a human gene
highly mutated in a variety of cancers. However, little is known about the characteristics of …

Background. An inflammatory process may be one of the critical factors that contribute to the
development of diabetic nephropathy (DN). We reported previously that intercellular …

As oxidative stress plays a crucial role in the development and pathogenesis of
hypertension, we analyzed the redox (reduction/oxidation) status in tissues from Wistar …

Patients suffering from depression frequently display hyperactivity of the hypothalamic–
pituitary–adrenal axis (HPA) resulting in elevated cortisol levels. One main symptom of this …

The exact antineoplastic effects of calcium and vitamin D3 in the human colon are unclear.
Animal and in vitro studies show that these two agents reduce oxidative stress; however …

Oxidative damage and inflammation are proposed to be involved in an age-related
functional decline of exocrine glands. However, the molecular mechanism of how oxidative …

Arsenic is widely distributed in nature in the form of either metalloids or chemical
compounds, which cause a variety of pathologic conditions including cutaneous and …

Even under the best of circumstances, DNA is constantly subjected to chemical
modifications. Several types of DNA damage such as SSB (single strand break), DSB …

Novel materials are often commercialized without a complete assessment of the risks they
pose to human health because such assessments are costly and time-consuming; …