Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network

JAHR Claassen… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral autoregulation is the intrinsic ability of the brain to maintain adequate cerebral
perfusion in the presence of blood pressure changes. A large number of methods to assess …

Cerebral blood flow and autoregulation: current measurement techniques and prospects for noninvasive optical methods

S Fantini, A Sassaroli, KT Tgavalekos… - …, 2016 - spiedigitallibrary.org
Cerebral blood flow (CBF) and cerebral autoregulation (CA) are critically important to
maintain proper brain perfusion and supply the brain with the necessary oxygen and energy …

Transcranial Doppler ultrasound: a review of the physical principles and major applications in critical care

J Naqvi, KH Yap, G Ahmad… - International journal of …, 2013 - Wiley Online Library
Transcranial Doppler (TCD) is a noninvasive ultrasound (US) study used to measure
cerebral blood flow velocity (CBF‐V) in the major intracranial arteries. It involves use of low …

Measuring cerebrovascular reactivity: what stimulus to use?

J Fierstra, O Sobczyk… - The Journal of …, 2013 - Wiley Online Library
Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory
or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between …

Cerebral autoregulation in stroke: a review of transcranial Doppler studies

MJH Aries, JW Elting, J De Keyser, BPH Kremer… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Cerebral autoregulation may become impaired after stroke. To
provide a review of the nature and extent of any autoregulation impairment after stroke and …

Cerebral autoregulation: an overview of current concepts and methodology with special focus on the elderly

AHEA Van Beek, JAHR Claassen… - Journal of Cerebral …, 2008 - journals.sagepub.com
Cerebral autoregulation (CA) refers to the properties of the brain vascular bed to maintain
cerebral perfusion despite changes in blood pressure (BP). Whereas classic studies have …

The cerebrovascular response to carbon dioxide in humans

A Battisti‐Charbonney, J Fisher… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary Two mechanisms control brain blood flow by changing blood
vessel diameter: autoregulation maintains flow in the face of perfusion pressure changes …

Hypertension, brain damage and cognitive decline

D Gąsecki, M Kwarciany, W Nyka… - Current hypertension …, 2013 - Springer
Loss of cognitive function is one the most devastating manifestations of ageing and vascular
disease. Cognitive decline is rapidly becoming an important cause of disability worldwide …

The relationship between blood pressure and cognitive function

V Novak, I Hajjar - Nature Reviews Cardiology, 2010 - nature.com
The relationship between blood pressure (BP) and cognitive outcomes in elderly adults has
implications for global health care. Both hypertension and hypotension affect brain perfusion …