[HTML][HTML] Mitochondrial ROS in myocardial ischemia reperfusion and remodeling

H Bugger, K Pfeil - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2020 - Elsevier
Despite major progress in interventional and medical treatments, myocardial infarction (MI)
and subsequent development of heart failure (HF) are still associated with high mortality …

[HTML][HTML] Ischemia/reperfusion injury revisited: an overview of the latest pharmacological strategies

ROS Soares, DM Losada, MC Jordani, P Évora… - International journal of …, 2019 - mdpi.com
Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

[HTML][HTML] The role of mitochondria in the mechanisms of cardiac ischemia-reperfusion injury

AV Kuznetsov, S Javadov, R Margreiter, M Grimm… - Antioxidants, 2019 - mdpi.com
Mitochondria play a critical role in maintaining cellular function by ATP production. They are
also a source of reactive oxygen species (ROS) and proapoptotic factors. The role of …

Shadow electrochemiluminescence microscopy of single mitochondria

Y Ma, C Colin, J Descamps, S Arbault… - Angewandte …, 2021 - Wiley Online Library
Mitochondria are the subcellular bioenergetic organelles. The analysis of their morphology
and topology is essential to provide useful information on their activity and metabolism …

[HTML][HTML] Acetylation of mitochondrial proteins in the heart: the role of SIRT3

RM Parodi-Rullán, XR Chapa-Dubocq… - Frontiers in …, 2018 - frontiersin.org
A growing number of studies have demonstrated the role of post-translational modifications
of proteins, particularly acetylation, in human diseases including neurodegenerative and …

[HTML][HTML] Apaf-1 pyroptosome senses mitochondrial permeability transition

W Xu, Y Che, Q Zhang, H Huang, C Ding, Y Wang… - Cell metabolism, 2021 - cell.com
Caspase-4 is an intracellular sensor for cytosolic bacterial lipopolysaccharide (LPS) and
underlies infection-elicited pyroptosis. It is unclear whether and how caspase-4 detects host …

[HTML][HTML] Pharmacological cardioprotection against ischemia reperfusion injury—the search for a clinical effective therapy

Q Wang, CJ Zuurbier, R Huhn, C Torregroza… - Cells, 2023 - mdpi.com
Pharmacological conditioning aims to protect the heart from myocardial ischemia-
reperfusion injury (IRI). Despite extensive research in this area, today, a significant gap …

[HTML][HTML] Mitochondria-targeted cyclosporin A delivery system to treat myocardial ischemia reperfusion injury of rats

C Zhang, Y Cheng, D Liu, M Liu, H Cui, B Zhang… - Journal of …, 2019 - Springer
Abstract Background Cyclosporin A (CsA) is a promising therapeutic drug for myocardial
ischemia reperfusion injury (MI/RI) because of its definite inhibition to the opening of …

[HTML][HTML] Dissecting the crosstalk between endothelial mitochondrial damage, vascular inflammation, and neurodegeneration in cerebral amyloid angiopathy and …

RM Parodi-Rullán, S Javadov, S Fossati - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the most prevalent cause of dementia and is pathologically
characterized by the presence of parenchymal senile plaques composed of amyloid β (Aβ) …

Mitochondria as potential targets and initiators of the blue light hazard to the retina

JX Tao, WC Zhou, XG Zhu - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Commercially available white light‐emitting diodes (LEDs) have an intense emission in the
range of blue light, which has raised a range of public concerns about their potential risks as …