Objective WWOX is an autosomal recessive cause of early infantile developmental and
epileptic encephalopathy (WWOX‐DEE), also known as WOREE (WWOX‐related epileptic …

The WWOX tumor suppressor gene is located at 16q23. 1–23.2, which covers the region of
FRA16D—a common fragile sites. Deletions within the WWOX coding sequence are …

We have constructed a high-resolution genomic microarray of human chromosome 16q, and
used it for comparative genomic hybridization analysis of 16 prostate tumors. We …

The WWOX (WW-domain containing oxidoreductase) is a candidate tumour suppressor
gene spanning the same chromosome region, 16q23, as the second most common fragile …

The WW domain-containing oxidoreductase (WWOX) encodes a tumor suppressor that is
frequently lost in many cancer types. Wwox-deficient mice develop normally but succumb to …

We demonstrate that comparative genomic hybridization (CGH) onto cDNA microarrays may
be used to carry out genome-wide screens for regions of genetic loss, including …

WWOX is a putative tumor suppressor gene that spans approximately a 1 Mb genomic
region and is the site for the second most common chromosomal fragile site, FRA16D at …

Non‐Hodgkin lymphomas (NHL) represent a frequent complication of human
immunodeficiency virus (HIV) infection. To elucidate HIV‐NHL pathogenesis, we performed …

It was hypothesized as early as 1986, that the recently discovered common fragile sites
could facilitate recombination events, such as deletions and translocations, that result in …

The WW domain-containing oxidoreductase (WWOX) gene encodes a 46-kDa tumor
suppressor. The Wwox protein contains two N-terminal WW domains that interact with …