[HTML][HTML] Neuropilins as potential biomarkers in hepatocellular carcinoma: a systematic review of basic and clinical implications

P Fernández-Palanca, T Payo-Serafín… - Clinical and …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common and deadly cancers worldwide
and is characterized by complex molecular carcinogenesis. Neuropilins (NRPs) NRP1 and …

Pan-cancer landscape of the RUNX protein family reveals their potential as carcinogenic biomarkers and the mechanisms underlying their action

S Pan, S Sun, B Liu, Y Hou - Journal of Translational Internal …, 2022 - degruyter.com
Background The RUNX family of transcription factors plays an important regulatory role in
tumor development. Although the importance of RUNX in certain cancer types is well known …

Roles of cuproptosis-related gene DLAT in various cancers: a bioinformatic analysis and preliminary verification on pro-survival autophagy

Q Yang, S Zeng, W Liu - PeerJ, 2023 - peerj.com
Background Studies have shown that the expressions and working mechanisms of
Dihydrolipoamide S-acetyltransferase (DLAT) in different cancers vary. It is necessary to …

Systematic interrogation of tumor cell resistance to chimeric antigen receptor T-cell therapy in pancreatic cancer

KR Hagel, R Arafeh, S Gang, TE Arnoff, RC Larson… - Cancer research, 2023 - AACR
Chimeric antigen receptor (CAR) T-cell therapy can lead to dramatic clinical responses in B-
cell malignancies. However, early clinical trials with CAR T-cell therapy in non–B-cell …

An integrative pan-cancer analysis of PBK in human tumors

H Wen, Z Chen, M Li, Q Huang, Y Deng… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: PDZ binding kinase (PBK) is a serine/threonine kinase, which belongs to the
mitogen-activated protein kinase kinase (MAPKK) family. It has been shown to be a critical …

Pan-cancer analysis of AIM2 inflammasomes with potential implications for immunotherapy in human cancer: A bulk omics research and single cell sequencing …

Y Qin, L Pan, T Qin, H Ruan, Y Zhang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The absent in melanoma 2 (AIM2) inflammasome is a multi-protein platform that
recognizes aberrant cytoplasmic double-stranded DNA (dsDNA) and induces cytokine …

BPTF in bone marrow provides a potential progression biomarker regulated by TFAP4 through the PI3K/AKT pathway in neuroblastoma

C Jiang, Y Yang, S He, Z Yue, T Xing, P Chu… - Biological Procedures …, 2023 - Springer
Background Neuroblastoma (NB) is the most common extracranial malignant solid tumor in
children, which is highly prone to bone marrow (BM) metastasis. BM can monitor early signs …

Bioinformatics analysis of prognostic value and immunological role of MeCP2 in pan-cancer

Y Wang, Y Zhang, F Wang, T Li, X Song, H Shi, J Du… - Scientific Reports, 2022 - nature.com
Abstract Methyl-CpG-binding protein 2 (MeCP2) is an important epigenetic regulatory factor
that promotes many tumor developments, such as liver cancer, breast cancer, and colorectal …

NR3C1 and NR3C2 Genes Increase the Risk of Suicide Attempt in Psychiatric Disorder Patients with History of Childhood Trauma

MA Sanabrais-Jiménez… - Neuropsychiatric …, 2023 - Taylor & Francis
Background Hypothalamic-pituitary-adrenal axis gene variants and childhood trauma (CT)
are considered risk factors for suicide attempt (SA). The aim of the present study was …

Role of SERCA3 in the Prognosis and Immune Function in Pan‐Cancer

J Li, X Li, H Huang, L Tao, C Zhang, Y Xie… - Journal of …, 2022 - Wiley Online Library
The sarcoendoplasmic reticulum calcium adenosine triphosphatase (ATPase) 3 (SERCA3),
a member of the SERCA protein family, is located at the endoplasmic reticulum. Its main …