Off balance: Interferons in COVID-19 lung infections

MA Akamatsu, JT de Castro, CY Takano, PL Ho - EBioMedicine, 2021 - thelancet.com
Interferons are innate and adaptive cytokines involved in many biological responses, in
particular, viral infections. With the final response the result of the balance of the different …

Advances on genetic and genomic studies of ALV resistance

G Mo, P Wei, B Hu, Q Nie, X Zhang - Journal of Animal Science and …, 2022 - Springer
Avian leukosis (AL) is a general term for a variety of neoplastic diseases in avian caused by
avian leukosis virus (ALV). No vaccine or drug is currently available for the disease …

[HTML][HTML] Chicken peripheral blood mononuclear cells response to avian leukosis virus subgroup J infection assessed by single-cell RNA sequencing

X Qu, X Li, Z Li, M Liao, M Dai - Frontiers in microbiology, 2022 - frontiersin.org
Chicken peripheral blood mononuclear cells (PBMCs) exhibit wide-ranging cell types, but
current understanding of their subclasses, immune cell classification, and function is limited …

[HTML][HTML] Transcriptome analysis of the uterovaginal junction containing sperm storage tubules in heat-stressed breeder hens

S Kubota, P Pasri, S Okrathok, O Jantasaeng… - Poultry Science, 2023 - Elsevier
Sperm storage tubules (SSTs) in the uterovaginal junction (UVJ) of the oviduct are major
sites of sperm storage after artificial insemination or mating. Female birds may regulate …

BmCH25H, a vertebrate interferon‐stimulated gene(ISG) homolog, inhibits BmNPV infection dependent on its hydroxylase activity in Bombyx mori

H Wu, J Xia, S Fei, Y Wang, M Zhang, Y Guo… - Insect …, 2023 - Wiley Online Library
Abstract Cholesterol‐25‐hydroxylase (CH25H) has been identified as an interferon‐
stimulated gene (ISG) in mammals that exerts its antiviral effects by catalyzing the …

Identification of a novel interferon lambda splice variant in chickens

J Chen, P Li, W Zou, Y Jiang, L Li, P Hao… - Journal of …, 2023 - Am Soc Microbiol
Type III interferons (IFNLs) have critical roles in the host's innate immune system, also
serving as the first line against pathogenic infections of mucosal surfaces. In mammals …

Avian cytokines and their receptors

AGD Bean, JW Lowenthal - Avian immunology, 2022 - Elsevier
With rapid advances being continually made in the field of avian immunology, new data is
constantly coming to light and enhancing our knowledge of key immunological molecules …

In Vitro Characterization of chIFITMs of Aseel and Kadaknath Chicken Breeds against Newcastle Disease Virus Infection

M Malarmathi, N Murali, M Selvaraju, K Sivakumar… - Biology, 2023 - mdpi.com
Simple Summary Aseel and Kadaknath are indigenous chicken breeds in India. Due to their
distinctiveness, these two breeds are becoming more important. Aseel has a reputation for …

[HTML][HTML] The IFN-γ receptor promotes immune dysregulation and disease in STING gain-of-function mice

WA Stinson, CA Miner, FR Zhao, AJ Lundgren… - JCI insight, 2022 - ncbi.nlm.nih.gov
STING gain-of-function mutations cause STING-associated vasculopathy with onset in
infancy (SAVI) in humans, a disease characterized by spontaneous lung inflammation and …

Chicken Interferon-Alpha and-Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells

J Lai, X He, R Zhang, L Zhang, L Chen, F He… - International Journal of …, 2024 - mdpi.com
Hydropericardium hepatitis syndrome (HHS) is primarily caused by fowl adenovirus
serotype 4 (FAdV-4), causing high mortality in chickens. Although vaccination strategies …