Intervertebral disc (IVD) degeneration is a major cause of low back pain, a prevalent and
chronic condition that has a striking effect on quality of life. Currently, no approved …

Non-specific low back pain affects people of all ages and is a leading contributor to disease
burden worldwide. Management guidelines endorse triage to identify the rare cases of low …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Exosome therapy is a promising therapeutic approach for intervertebral disc degeneration
(IVDD) and achieves its therapeutic effects by regulating metabolic disorders, the …

Background Low back pain is the leading cause of years lived with disability globally, but
most interventions have only short-lasting, small to moderate effects. Cognitive functional …

Low back pain is the leading cause for years lived in disability. Most people with acute low
back pain improve rapidly, but 4% to 25% of patients become chronic. Since the previous …

A systematic review of the available evidence examining the cost of work-related stress
(WRS) would yield important insights into the magnitude of this social phenomenon. The …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

The burden of neurological disease in the United States: A summary report and call to action. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

Musculoskeletal disorders (MSDs) are the leading cause of work disability, sickness
absence from work,'presenteeism'and loss of productivity across all the European Union …