Mechanisms of corticosteroid resistance in severe asthma and chronic obstructive pulmonary disease (COPD)

IM Adcock, J Marwick, P Casolari… - Current …, 2010 - ingentaconnect.com
Inhaled glucocorticoids, also know as corticosteroids (ICS), revolutionized the treatment of
asthma by suppressing airways inflammation and ICS therapy now forms the basis of …

[引用][C] 支气管哮喘气道重塑的研究进展

潘亦林, 朱燕亭, 李满祥 - 中华肺部疾病杂志: 电子版, 2015

Coordinated DNA methylation and gene expression data for identification of the critical genes associated with childhood atopic asthma

K Shi, M Ge, X Chen - Journal of Computational Biology, 2020 - liebertpub.com
Asthma is a chronic inflammatory disorder of airways that involves in many cells and factors.
This study aimed to screen critical genes and miRNAs involved in childhood atopic asthma …

Insights into the epigenetics of chronic rhinosinusitis with and without nasal polyps: a systematic review

T Brar, L Marks, D Lal - Frontiers in Allergy, 2023 - frontiersin.org
Background Epigenetics facilitates insights on the impact of host environment on the
genesis of chronic rhinosinusitis (CRS) through modulations of host gene expression and …

[HTML][HTML] Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation

SU Lee, KS Ahn, MH Sung, JW Park, HW Ryu… - Molecules and cells, 2014 - Elsevier
The β 2 adrenergic receptor (ADRB2) is a G protein-coupled transmembrane receptor
expressed in the human respiratory tract and widely recognized as a pharmacological target …

Inhibition of NADPH oxidase-derived reactive oxygen species decreases expression of inflammatory cytokines in A549 cells

J Wieczfinska, P Sitarek, E Skała, T Kowalczyk… - Inflammation, 2019 - Springer
Various experimental models strongly support the hypothesis that airway inflammation can
be caused by oxidative stress. Inflammatory airway diseases like asthma and COPD are …

[HTML][HTML] Respiratory protective effects of Korean red ginseng in a mouse model of particulate matter 4-induced airway inflammation

WK Yang, SW Kim, SH Youn, SH Hyun, CK Han… - Journal of Ginseng …, 2023 - Elsevier
Background Air pollution has led to an increased exposure of all living organisms to fine
dust. Therefore, research efforts are being made to devise preventive and therapeutic …

Characterization of antimicrobial, cytotoxic, and antiendotoxin properties of short peptides with different hydrophobic amino acids at “a” and “d” positions of a heptad …

S Azmi, S Srivastava, NN Mishra… - Journal of medicinal …, 2013 - ACS Publications
To understand the influence of different hydrophobic amino acids at “a” and “d” positions of a
heptad repeat sequence on antimicrobial, cytotoxic, and antiendotoxin properties, four 15 …

Nanocurcumin modulates Th17 cell responses in moderate and severe COPD patients

A Mardi, S Abdolmohammadi-Vahid, SA Sadeghi… - Heliyon, 2024 - cell.com
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory process in the
airways that results in airflow obstruction. It is mainly linked to cigarette smoke exposure …

Inhibitory effects of Cnidium monnieri fruit extract on pulmonary inflammation in mice induced by cigarette smoke condensate and lipopolysaccharide

HG Kwak, HB Lim - Chinese journal of natural medicines, 2014 - Elsevier
The aim of this study was to investigate the inhibitory effect of Cnidium monnieri fruit (CM)
extracts on pulmonary inflammation induced in mice by cigarette smoke condensate (CSC) …