Inhibitory effects of Cnidium monnieri fruit extract on pulmonary inflammation in mice induced by cigarette smoke condensate and lipopolysaccharide

HG Kwak, HB Lim - Chinese journal of natural medicines, 2014 - Elsevier
The aim of this study was to investigate the inhibitory effect of Cnidium monnieri fruit (CM)
extracts on pulmonary inflammation induced in mice by cigarette smoke condensate (CSC) …

Pharmacotherapy of critical asthma syndrome: current and emerging therapies

TE Albertson, M Schivo, N Gidwani, NJ Kenyon… - Clinical reviews in …, 2015 - Springer
The critical asthma syndrome (CAS) encompasses the most severe, persistent, refractory
asthma patients for the clinician to manage. Personalized pharmacotherapy is necessary to …

[HTML][HTML] Decoding LncRNA in COPD: Unveiling Prognostic and Diagnostic Power and Their Driving Role in Lung Cancer Progression

O Sweef, R Mahfouz, T Taşcıoğlu… - International Journal of …, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) and lung cancer represent formidable
challenges in global health, characterized by intricate pathophysiological mechanisms and …

Novel therapies in asthma: leukotriene antagonists, biologic agents, and beyond

ES Papierniak, DT Lowenthal… - American journal of …, 2013 - journals.lww.com
Asthma is one of the most common conditions seen in clinical practice and carries both a
significant disease burden in terms of patient morbidity and a high economic burden in both …

An update on emerging drugs for asthma

GM Walsh - Expert Opinion on Emerging Drugs, 2012 - Taylor & Francis
Introduction: It is recognized that airway inflammation is key to asthma pathogenesis.
Biopharmaceutical approaches have identified new therapies that target key cells and …

Intravenous immunoglobulin attenuates airway hyperresponsiveness in a murine model of allergic asthma

GN Kaufman, AH Massoud… - Clinical & …, 2011 - Wiley Online Library
Background Intravenous immunoglobulin (IVIG) has potent anti‐inflammatory and immune‐
modulating properties. IVIG has been utilized as a steroid‐sparing agent in severe asthma …

Anti-TNF inhibits the airways neutrophilic inflammation induced by inhaled endotoxin in human

O Michel, PHD Dinh, V Doyen, F Corazza - BMC Pharmacology and …, 2014 - Springer
Background Inhaled endotoxin induces airways' neutrophilia, in human. TNF-a being a key
cytokine in the response to endotoxin, the effect of anti-TNF on the endotoxin-induced …

Tristetraprolin down-regulation contributes to persistent TNF-alpha expression induced by cigarette smoke extract through a post-transcriptional mechanism

XK Zhao, P Che, ML Cheng, Q Zhang, M Mu, H Li… - PLoS …, 2016 - journals.plos.org
Rationale Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its
expression is up-regulated in chronic obstructive pulmonary disease (COPD). Tristetraprolin …

[HTML][HTML] Inflammatory effects induced by selected limonene oxidation products: 4-OPA, IPOH, 4-AMCH in human bronchial (16HBE14o-) and alveolar (A549) epithelial …

D Lipsa, P Leva, J Barrero-Moreno, M Coelhan - Toxicology Letters, 2016 - Elsevier
Limonene, a monoterpene abundantly present in most of the consumer products (due to its
pleasant citrus smell), easily undergoes ozonolysis leading to several limonene oxidation …

Animal models in chronic obstructive pulmonary disease—an overview

MY Marcelino, NL Fuoco, CA Faria… - Experimental Lung …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is characterized by progressive airway
obstruction resultant from an augmented inflammatory response of the respiratory tract to …