How to use biologic agents in patients with rheumatoid arthritis who have comorbid disease

JS Richards, SM Dowell, ME Quinones, GS Kerr - Bmj, 2015 - bmj.com
Although biologic disease modifying anti-rheumatic drugs (bDMARDs) have improved the
quality of life of patients with rheumatoid arthritis, side effects remain a problem, especially …

TNFα-blockade stabilizes local airway hyperresponsiveness during TLR-induced exacerbations in murine model of asthma

M Starkhammar, S Kumlien Georén, SE Dahlén… - Respiratory …, 2015 - Springer
Viral infections are a common cause of asthma exacerbation. These maladies are
sometimes complicated by bacterial infections. Toll-like receptors (TLRs) are in the forefront …

Tumor Necrosis Factor-α (-308G> A) Gene Polymorphism and Its Association with Asthma and Atopy Status

A Razaghian, N Parvaneh… - Iranian Journal of …, 2023 - publish.kne-publishing.com
Asthma is one of the most prevalent chronic lung diseases that afflict genetically
predisposed individuals. Certain cytokine gene polymorphisms have been associated with …

Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling

JY Cho, A Pham, P Rosenthal, M Miller… - International …, 2011 - Elsevier
The role of tumor necrosis factor-α (TNF-α) in contributing to allergen induced airway
remodeling in asthma is unknown. In this study we have utilized a mouse model of chronic …

Probing cellular and molecular mechanisms of cigarette smoke-induced immune response in the progression of chronic obstructive pulmonary disease using …

Z Pan, H Yu, JL Liao - PLoS One, 2016 - journals.plos.org
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder
characterized by progressive destruction of lung tissues and airway obstruction. COPD is …

Emerging drugs for chronic obstructive pulmonary disease

MG Matera, L Calzetta, A Segreti… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is a major public health
problem with increasing morbidity and mortality. It is characterized by airflow obstruction that …

TNF-α− 308 G/A variant and susceptibility to chronic obstructive pulmonary disease: a systematic review and meta-analysis

MS Asl, A Ahmadi, J Salimian, S Shohani… - Cytokine, 2019 - Elsevier
Background and objective TNF-α− 308 G/A variant is recognized to play an important role in
the pathogenesis of chronic obstructive pulmonary disease (COPD). Although many studies …

Tumor necrosis factor alpha-mediated asthma?

T Nabe - International archives of allergy and immunology, 2013 - karger.com
According to established knowledge, the mechanisms of allergic asthma are as follows:
when an inhaled allergen penetrates the airway epithelium, it is detected by dendritic cells …

Management of severe asthma exacerbation in children

XF Wang, JG Hong - World Journal of Pediatrics, 2011 - Springer
Background Asthma is a common disease in children and acute severe asthma
exacerbation can be life-threatening. This article aims to review recent advances in …

[引用][C] 下呼吸道流感嗜血杆菌定植对哮喘小鼠气道炎症的影响及信号通路的研究

康建强, 董杨阳, 杨玲, 宋珍, 范嘉盈 - 诊断学理论与实践, 2020