Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing
serious nosocomial infections, which is considered as the most threatening Gram-negative …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

INTRODUCTION Despite their key biological roles, only a few proteins that fold into lipid
membranes have been designed de novo. A class of membrane proteins—transmembrane …

Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …

The integration of β-barrel proteins into the bacterial outer membrane (OM) is catalysed by
the β-barrel assembly machinery (BAM). The central BAM subunit (BamA) itself contains a β …

In mitochondria, β-barrel outer membrane proteins mediate protein import, metabolite
transport, lipid transport, and biogenesis. The Sorting and Assembly Machinery (SAM) …

Myxobacterial predation on bacteria has been investigated for several decades. However,
their predation on fungi has received less attention. Here, we show that a novel outer …

Single-molecule force spectroscopy is a unique method that can probe the structural
changes of single proteins at a high spatiotemporal resolution while mechanically …

The cell envelope is essential for the survival of Gram-negative bacteria. This specialised
membrane is densely packed with outer membrane proteins (OMPs), which perform a …

Prior to the nineteenth century, infectious disease was one of the leading causes of death.
Human life expectancy has roughly doubled over the past century as a result of the …