Peripheral markers of depression
A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …
medical and socioeconomic burden. There is a growing interest in the biological …
Depression as a microglial disease
Despite decades of intensive research, the biological mechanisms that causally underlie
depression are still unclear, and therefore the development of novel effective antidepressant …
depression are still unclear, and therefore the development of novel effective antidepressant …
A review of depression and suicide risk assessment using speech analysis
This paper is the first review into the automatic analysis of speech for use as an objective
predictor of depression and suicidality. Both conditions are major public health concerns; …
predictor of depression and suicidality. Both conditions are major public health concerns; …
Treatment-resistant depression and peripheral C-reactive protein
SR Chamberlain, J Cavanagh, P De Boer… - The British Journal of …, 2019 - cambridge.org
BackgroundC-reactive protein (CRP) is a candidate biomarker for major depressive disorder
(MDD), but it is unclear how peripheral CRP levels relate to the heterogeneous clinical …
(MDD), but it is unclear how peripheral CRP levels relate to the heterogeneous clinical …
The role of pro-inflammatory cytokines in neuroinflammation, neurogenesis and the neuroendocrine system in major depression
YK Kim, KS Na, AM Myint, BE Leonard - Progress in Neuro …, 2016 - Elsevier
Cytokines are pleiotropic molecules with important roles in inflammatory responses. Pro-
inflammatory cytokines and neuroinflammation are important not only in inflammatory …
inflammatory cytokines and neuroinflammation are important not only in inflammatory …
Blood-brain barrier regulation in psychiatric disorders
J Kealy, C Greene, M Campbell - Neuroscience letters, 2020 - Elsevier
The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …
and the cerebral parenchyma, controlling the transport of material to and from the brain …
Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer
W Chen, F Liu, Z Ling, X Tong, C Xiang - PloS one, 2012 - journals.plos.org
Recent reports have suggested the involvement of gut microbiota in the progression of
colorectal cancer (CRC). We utilized pyrosequencing based analysis of 16S rRNA genes to …
colorectal cancer (CRC). We utilized pyrosequencing based analysis of 16S rRNA genes to …
MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy
B Vafadari, A Salamian… - Journal of …, 2016 - Wiley Online Library
Abstract Matrix metalloproteinase‐9 (MMP‐9) is a member of the metzincin family of mostly
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
extracellularly operating proteases. Despite the fact that all of these enzymes might be target …
The blood–brain barrier in psychosis
Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …
neurological disorders, but much less is known about the role of the blood–brain barrier in …
Chemokines in depression in health and in inflammatory illness: a systematic review and meta-analysis
SP Leighton, L Nerurkar, R Krishnadas… - Molecular …, 2018 - nature.com
Inflammatory illness is associated with depression. Preclinical work has shown that
chemokines are linked with peripheral–central crosstalk and may be important in mediating …
chemokines are linked with peripheral–central crosstalk and may be important in mediating …