Introduction The adipokines leptin and adiponectin have been associated with
atherosclerosis and the risk of cerebral infarcts. Pre-clinical studies, however, suggest a …

Inhibitory control, the ability to suppress prepotent responses and resist irrelevant stimuli, is
thought to play a critical role in the maintenance of obesity. However, electrophysiological …

Background Despite the accumulating research efforts, the current treatment of Alzheimer's
disease (AD) remains far from achieving any clinical success in modifying the underlying …

It has been established that diabetes mellitus (DM) is a risk factor for dementia, and recent
studies have clearly shown that dementia is one of the complications of DM. The increase of …

Background Animal studies provide strong evidence that the CNS directly regulates bone
remodeling through the actions of the hypothalamus via two distinct pathways, the neural …

Nowadays, the amyloid cascade hypothesis is the dominant model to explain Alzheimer's
disease (AD) pathogenesis. By this hypothesis, the inherited genetic form of AD is …

Preterm infants face lifelong disabilities, including learning disorders, as well as visual,
auditory and behavioral problems. Recent studies have demonstrated that leptin, an …

Background: Metabolic dysfunction links to cognitive deficits in Alzheimer's disease (AD).
Leptin is an anti-obesity hormone that modulates energy homeostasis and memory function …

Background: There is growing interest in the pathophysiological processes of preclinical
Alzheimer's disease (AD), including the potential role of leptin. Human studies have shown …

Background: US studies suggest that leptin, a fat-derived hormone, may be protective
against the development of dementia. Objective: To investigate the complex relationship …